Results 311 to 320 of about 1,387,703 (389)

Quantitative Investigation of Nitrosamine Drug Substance‐Related Impurities (NDSRIs) Under Artificial Gastric Conditions by Liquid Chromatography–Tandem Mass Spectrometry and Structure–Activity Relationship Analysis

Drug Testing and Analysis, EarlyView.
The study provides information about the impact of physiological gastric conditions on the unbeneficial occurrence of nitrosamine drug substance–related impurities (NDSRIs). Both main factors for nitrosation in the form of acidic conditions and the presence of nitrite were adequately chosen for triggering the conversion of drug compounds into NDSRIs ...
Matthias Vogel, Sylvia E. Escher, Emanuel Weiler, Anke Londenberg, Uwe Deppenmeier, Rhys Whomsley   +5 more
wiley   +1 more source

Pre-Exercise Caffeine and Sodium Bicarbonate: Their Effects on Isometric Mid-Thigh Pull Performance in a Crossover, Double-Blind, Placebo-Controlled Study. [PDF]

Sports (Basel)
Kaçoğlu C, Kirkaya İ, Ceylan Hİ, de Assis GG, Almeida-Neto P, Bayrakdaroğlu S, Chaves Oliveira C, Özkan A, Nikolaidis PT.   +8 more
europepmc   +1 more source

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T‐tubule pH regulation

Developmental Dynamics, EarlyView.
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel, Maya Silver, Aaron H. Wasserman, Samantha Rea, Charles C. Hong, Charles H. Williams   +5 more
wiley   +1 more source

Magnesium sulphate and sodium bicarbonate as additives for periarticular local infiltration analgesia improve pain management after unicompartmental knee arthroplasty: a prospective, double-blind, randomized controlled trial. [PDF]

J Orthop Surg Res
Zhu Y, Shen S, Cui L, Wu L, Zhang B.
europepmc   +1 more source

The Primary Moral Problem in Pernicious Vomiting in Pregnancy [PDF]

, 1938
Latchford, J. K.
core   +1 more source

From Salar to Cells: Validating Brine‐Sourced Li2CO3 from Salar de Uyuni for Lithium‐Ion Battery Cell Manufacture

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study demonstrates the viability of lithium carbonate sourced from Bolivia's Salar de Uyuni brine for use in lithium‐ion battery cathode manufacturing. Brine‐derived NMC111 cathodes were evaluated at commercially relevant mass loadings and in large‐format pouch cell configurations, confirming their industrial compatibility and performance. In this
Satish Bolloju, Edgar Bautista Quisbert, Gerard Bree, Gaurav C. Pandey, Galo J. Páez Fajardo, Matthew J. W. Ogley, Ashok S. Menon, Paola Patiño Gutiérrez, Danitza Delgado Bobarin, Sanghamitra Moharana, Muhammad Ans, Eleni Fiamegkou, Rebecca A. Sellers, Louis F. J. Piper   +13 more
wiley   +1 more source

Pre‐admission beta‐blocker therapy and outcomes in cardiogenic shock: Insights from the Altshock‐2 Registry

ESC Heart Failure, EarlyView.
Among 668 with cardiogenic shock included in the multicentre prospective Altshock‐2 registry, 299 patients (44.8%) received pre‐admission beta‐blocker therapy. Previous beta‐blocker therapy influenced the early hemodynamic response to vasoactive drugs, but it was not associated with in‐hospital mortality.
Matteo Pagnesi, Mauro Riccardi, Alice Sacco, Giovanni Tavecchia, Giovanna Viola, Simone Frea, Martina Briani, Letizia Fausta Bertoldi, Maurizio Bertaina, Luciano Potena, Serafina Valente, Marco Marini, Gaetano Maria De Ferrari, Nicoletta D'Ettore, Astrid Cardinale, Rita Camporotondo, Matteo Rota, Guido Tavazzi, Nuccia Morici, Federico Pappalardo, Marco Metra, on behalf of the Altshock‐2 investigators   +21 more
wiley   +1 more source

Alkalinization Using Sodium Bicarbonate for COVID-19 Treatment: A Systematic Review and Meta-Analysis. [PDF]

J Evid Based Integr Med
Shafiee A, Jafarabady K, Moltazemi H, Amini MJ, Rafiei MA, Akhondi A, Mozhgani SH.   +6 more
europepmc   +1 more source

Efficacy of ambulatory intravenous diuresis for chronic heart failure patients: Insights from the DEA‐HF trial

ESC Heart Failure, EarlyView.
Graphical presentation of the study design, main results and conclusion. Abbreviations: Y/O = year old; HFpEF = heart failure with preserved ejection fraction; Kg = kilograms; NYHA = New York Heart Association; ACE = angiotensin‐converting enzyme; ARB = angiotensin receptor blockers; ARNI = angiotensin receptor‐neprilysin inhibitor; SGLT2i = sodium ...
Amit Gruber, Aharon (Ronnie) Abbo, Ina Volis, Doron Aronson, Nicolas Girerd, Søren Lund Kristensen, Robert Zukermann, Natalia Alberkant, Elena Sitnitsky, Anton Kruger, Polina Khasis, Evgeny Bravo, Boaz Elad, Ludmila Helmer Levin, Oren Caspi   +14 more
wiley   +1 more source