Results 41 to 50 of about 366,375 (330)

Zero balance ultrafiltration using dialysate during nationwide bicarbonate shortage: a retrospective analysis

open access: yesJournal of Cardiothoracic Surgery, 2019
Background Zero balance ultrafiltration (Z-BUF) utilizing injectable 8.4% sodium bicarbonate is utilized to treat hyperkalemia and metabolic acidosis associated with cardiopulmonary bypass (CPB).
Ryan Mullane   +7 more
doaj   +1 more source

Contrast-associated acute kidney injury : does it really exist, and if so, what to do about it? [PDF]

open access: yes, 2019
For decades, when contrast agents are administrated, physicians have been concerned because of the risk of inducing acute kidney injury (AKI). Recent literature questions the existence of AKI induced by contrast, but animal studies clearly showed harmful
Hoste, Eric, Vandenberghe, Wim
core   +2 more sources

Prophylactic perioperative sodium bicarbonate to prevent acute kidney injury following open heart surgery: a multicenter double-blinded randomized controlled trial. [PDF]

open access: yesPLoS Medicine, 2013
Preliminary evidence suggests a nephroprotective effect of urinary alkalinization in patients at risk of acute kidney injury. In this study, we tested whether prophylactic bicarbonate-based infusion reduces the incidence of acute kidney injury and ...
Michael Haase   +9 more
doaj   +1 more source

Acidose metabólica na infância: por que, quando e como tratá-la? [PDF]

open access: yes, 2007
Objectives: To critically discuss the treatment of metabolic acidosis and the main mechanisms of disease associated with this disorder; and to describe controversial aspects related to the risks and benefits of using sodium bicarbonate and other ...
Andrade, Olberes Vitor Braga de   +2 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Manufacturing of coir fibre-reinforced polymer composites by hot compression technique [PDF]

open access: yes, 2015
This present chapter describes the manufacturing technique and properties of coir fibre-reinforced polypropylene composites manufactured using a hot press machine.
Hasan, Mahbub   +4 more
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Texture profile of surimi-like material from mechanically deboned turkey meat

open access: yesBrazilian Journal of Food Technology, 2021
The study aimed to evaluate the textural properties of turkey surimi-like (TSL) gels from mechanically deboned turkey meat (MDTM) by washing procedures.
Armando Abel Massingue   +6 more
doaj   +1 more source

Pseudohypoaldosteronism type 1 due to novel variants of SCNN1B gene. [PDF]

open access: yes, 2016
UnlabelledAutosomal recessive pseudohypoaldosteronism type 1 (PHA1) is a rare disorder characterized by sodium wasting, failure to thrive, hyperkalemia, hypovolemia and metabolic acidosis.
Abraham, Smita B   +9 more
core   +2 more sources

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