A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Background: Sodium bicarbonate supplementation is a mainstay in the treatment of metabolic acidosis in patients with chronic kidney disease (CKD). Recent studies showed reduction of progression of CKD and reduced all-cause mortality.
Martina Gaggl +8 more
doaj +1 more source
Effects of creatine and sodium bicarbonate co-ingestion on multiple indices of mechanical power output during repeated wingate tests in trained men [PDF]
This study investigated the effects of creatine and sodium bicarbonate co-ingestion on mechanical power during repeated sprints. Nine well-trained men (age = 21.6 ± 0.9 yr, stature = 1.82 ± 0.05 m, body mass = 80.1 ± 12.8 kg) participated in a double ...
Griffen, Corbin +3 more
core +1 more source
Biomass Native Structure Into Functional Carbon‐Based Catalysts for Fenton‐Like Reactions
This study indicates that eight biomasses with 2D flaky and 1D acicular structures influence surface O types, morphology, defects, N doping, sp2 C, and Co nanoparticles loading in three series of carbon, N‐doped carbon, and cobalt/graphitic carbon. This work identifies how these structural factors impact catalytic pathways, enhancing selective electron
Wenjie Tian +7 more
wiley +1 more source
Adding 0.3% sodium sulphate or 0.3% sodium bicarbonate to corn-rape seed meal type diet with low levels of sulphur-containing amino acid and lysine for ISA brown laying hens, egg laying rate, egg weight and feed efficiency increased, profit per hen also ...
YIN Zhao-zheng +2 more
doaj +1 more source
Dissolved oxygen sensing using an optical fibre long period grating coated with hemoglobin [PDF]
A long period grating fiber optic sensor coated with hemoglobin is used to detect dissolved oxygen. The sensitivity of this sensor to the ratio of dissolved carbon dioxide to dissolved oxygen is demonstrated via the conversion of carboxyhemoglobin to
James, Stephen W. +2 more
core +1 more source
From Waste to Value: Conversion of Calcium Sulfate to Vaterite via Carbon Capture and Storage
This study introduces a new concept for carbon management that relies on the carbonation of industrial gypsum waste and yields phase‐pure vaterite at ambient conditions without any additives. The obtained vaterite is further shown to be a reactive material that develops compressive strength in aqueous suspensions like conventional cements.
Carlos Pimentel +4 more
wiley +1 more source
pH and salivary sodium bicarbonate in cancer patients : correlation with seric concentration [PDF]
Objective: To determine the correlation between pH and bicarbonate of soda in blood and saliva in child and adolescent patients during the administration of 3g/m2 of methotrexate.
Chaparro, Neira +4 more
core
Sodium bicarbonate and high-intensity-cycling capacity: variability in responses [PDF]
Purpose: The aim of this study was to determine whether gastrointestinal (GI) distress affects the ergogenicity of sodium bicarbonate and whether the degree of alkalaemia or other metabolic responses are different between individuals who improve exercise
Batterham AM +18 more
core +1 more source
Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting
A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar +4 more
wiley +1 more source

