Results 101 to 110 of about 241,355 (307)

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

open access: yesAdvanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini   +15 more
wiley   +1 more source

Generation of Oxygen Free Radicals by Proflavine: Implication in Protein Degradation

open access: yesHayati Journal of Biosciences, 2018
Proflavine, an acridine dye, is a known DNA intercalating agent. In the present study, we show that proflavine alone on photoillumination can generate reactive oxygen species (ROS).
Mansour K.M. Gatasheh   +3 more
doaj   +1 more source

Apollo-Soyuz pamphlet no. 2: X-rays, gamma-rays [PDF]

open access: yes, 1977
The nature of high energy radiation and its penetration through earth's atmosphere is examined with emphasis on X-rays, gamma rays, and cosmic radiation and the instruments used in their detection.
From, T. P., Page, L. W.
core   +1 more source

One-pot radioiodination of aryl amines via stable diazonium salts: preparation of 125I-imaging agents [PDF]

open access: yes, 2017
An operationally simple, one-pot, two-step tandem procedure that allows the incorporation of radioactive iodine into aryl amines via stable diazonium salts is described.
Luthra, Sajinder K.   +4 more
core   +2 more sources

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni   +15 more
wiley   +1 more source

Use of a distant reporter group as evidence for a conformational change in a sensory receptor [PDF]

open access: yes, 1977
A highly sensitive method for demonstrating ligand-induced conformational changes in protein molecules in solution is described. The method utilizes an environmentally sensitive reporter group that is known to be distant from the active site.
Hartig, P. R.   +2 more
core  

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao   +8 more
wiley   +1 more source

Unilateral breast uptake of Tc-99m pertechnetate in a patient with cold nodule of the thyroid

open access: yesWorld Journal of Nuclear Medicine, 2012
Common causes of unilateral breast uptake of Tc-99m pertechnetate are predominant breast-feeding on one side, mastitis, and breast cancer. Uptake of Tc-99m pertechnetate in the epithelial cells of the breast, like that of iodide, depends on the ...
Shankaramurthy Gayana   +3 more
doaj   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij   +8 more
wiley   +1 more source

4-Bromo-3-methoxy-1-phenyl-1H-pyrazole

open access: yesMolbank, 2009
The title compound was prepared by treatment of 4-bromo-1-phenyl-1H-pyrazol-3-ol with sodium hydride/methyl iodide in good yield. Detailed spectroscopic data (1H NMR, 13C NMR, 15N NMR, IR, MS) are presented.
Algirdas Šačkus   +3 more
doaj   +1 more source

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