Background Sodium/iodide symporter (NIS) mediates the active transport and accumulation of iodide from the blood into the thyroid gland. His-226 located in the extracellular region of NIS has been demonstrated to be critical for iodide transport in our ...
Liang Ji-An +5 more
doaj +1 more source
Tumor microenvironment affects exogenous sodium/iodide symporter expression
For decades, sodium/iodide symporter NIS-mediated iodide uptake has played a crucial role in the radioactive ablation of thyroid cancer cells. NIS-based gene therapy has also become a promising tool for the treatment of tumors of extrathyroidal origin ...
Fabio Castillo-Rivera +9 more
doaj +1 more source
Simple oxidation of pyrimidinylhydrazones to triazolopyrimidines and their inhibition of Shiga toxin trafficking [PDF]
The oxidative cyclisation of a range of benzothieno[2,3-d]pyrimidine hydrazones (7a–j) to the 1,2,4-triazolo[4,3-c]pyrimidines (8a–j) catalysed by lithium iodide or to the 1,2,4-triazolo[1,5-c]pyrimidines (10a–j) with sodium carbonate is presented.
Ahmed +46 more
core +1 more source
A matéria orgânica leve tem se mostrado um indicador precoce das mudanças na matéria orgânica do solo (MOS) acarretadas por diferentes usos e sistemas de manejo.
Michelle Sales Moreira Demolinari +4 more
doaj +1 more source
Advances in the design and development of oncolytic measles viruses. [PDF]
A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian +2 more
core +1 more source
A Simple and Effective Protocol for One-Pot Diazotization-Iodination of Aromatic Amines by Acidic Ionic Liquid [H-NMP]HSO4 at Room Temperature [PDF]
A simple and efficient one-pot method for the preparation of aromatic iodides has been developed by sequential diazotization–iodination of aromatic amines employing sodium nitrite and sodium iodide in the presence of acidic ionic liquid N-methyl-2 ...
Abdolreza Hajipour +1 more
doaj
A role for the small GTPases RAC1 and RAC1b in the modulation of NIS expression: potentiation of therapy with radioactive iodine in differentiated thyroid carcinoma [PDF]
Introduction or Background: The Sodium Iodide Symporter (NIS) is responsible for active transport of iodide into thyroid follicular cells. The retention of its functional expression in most of the well-differentiated thyroid carcinomas (DTCs) enables ...
Bugalho, Maria J. +5 more
core +1 more source
Ion-selective carbon-paste electrodes for halides and silver(I) ions [PDF]
The behaviour of a simple type of ion-selective electrode for halogens and silver has been studied. The electrode consists of a plastic body filled with carbon paste, the surface of which can be easily renewed.
Dahmen, E.A.M.F., Mesaric, S.
core +3 more sources
Betaine (trimethylammonioacetate) binary compound with sodium iodide
In the title compound, catena-poly[[[bis[2-(trimethylazaniumyl)acetato-κO]sodium]-di-μ-aqua-[diaquasodium]-di-μ-aqua] diiodide], {[Na2(C5H11NO2)2(H2O)6]I2}n, both Na+ ions have distorted octahedral environments (coordination number 6).
Alexander Y. Nazarenko
doaj +1 more source
The use of sodium iodide for the management of bovine respiratory disease [PDF]
Objective: The purpose of these studies was to (1) determine the effect of a single dose of oral sodium iodide on weaned beef calves and (2) determine the outcome of clinical application of a single dose of oral sodium iodide as an on arrival procedure ...
Shoemake, Brian McMillan
core +1 more source

