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Pro-tumorigenic non-pump function of sodium iodide symporter: A reimagined Trojan horse? [PDF]
Feng F, Yehia L, Eng C.
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Food & Function, 2021
Radioactive iodine (RAI) is commonly used to treat differentiated thyroid cancer (DTC). A major challenge is the dedifferentiation of DTC with the loss of radioiodine uptake.
Li Zhang+7 more
semanticscholar +1 more source
Radioactive iodine (RAI) is commonly used to treat differentiated thyroid cancer (DTC). A major challenge is the dedifferentiation of DTC with the loss of radioiodine uptake.
Li Zhang+7 more
semanticscholar +1 more source
The FASEB Journal, 2021
The sodium/iodide symporter (NIS) expresses at the basolateral plasma membrane of the thyroid follicular cell and mediates iodide accumulation required for normal thyroid hormonogenesis.
Mariano Martín+9 more
semanticscholar +1 more source
The sodium/iodide symporter (NIS) expresses at the basolateral plasma membrane of the thyroid follicular cell and mediates iodide accumulation required for normal thyroid hormonogenesis.
Mariano Martín+9 more
semanticscholar +1 more source
Thyroid, 2021
BACKGROUND The sodium/iodide symporter (NIS) mediates active iodide accumulation in the thyroid follicular cell. Autosomal recessive iodide transport defect (ITD)-causing loss-of-function NIS variants lead to dyshormonogenic congenital hypothyroidism due
Carlos Eduardo Bernal Barquero+7 more
semanticscholar +1 more source
BACKGROUND The sodium/iodide symporter (NIS) mediates active iodide accumulation in the thyroid follicular cell. Autosomal recessive iodide transport defect (ITD)-causing loss-of-function NIS variants lead to dyshormonogenic congenital hypothyroidism due
Carlos Eduardo Bernal Barquero+7 more
semanticscholar +1 more source