Results 231 to 240 of about 22,958 (276)

Genetic Defects in Thyroid Hormone Supply. [PDF]

open access: yes, 2014
FENZI, GIANFRANCO   +2 more
core  

Preclinical efficacy of the oncolytic measles virus expressing the sodium iodide symporter in iodine non-avid anaplastic thyroid cancer: a novel therapeutic agent allowing noninvasive imaging and radioiodine therapy

open access: bronze, 2012
Honey V. Reddi   +9 more
openalex   +1 more source
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Curcumin enhances the membrane trafficking of the sodium iodide symporter and augments radioiodine uptake in dedifferentiated thyroid cancer cells via suppression of the PI3K-AKT signaling pathway.

Food & Function, 2021
Radioactive iodine (RAI) is commonly used to treat differentiated thyroid cancer (DTC). A major challenge is the dedifferentiation of DTC with the loss of radioiodine uptake.
Li Zhang   +7 more
semanticscholar   +1 more source

The PDZ protein SCRIB regulates sodium/iodide symporter (NIS) expression at the basolateral plasma membrane

The FASEB Journal, 2021
The sodium/iodide symporter (NIS) expresses at the basolateral plasma membrane of the thyroid follicular cell and mediates iodide accumulation required for normal thyroid hormonogenesis.
Mariano Martín   +9 more
semanticscholar   +1 more source

An intramolecular ionic interaction linking defective sodium/iodide symporter transport to the plasma membrane and dyshormonogenic congenital hypothyroidism.

Thyroid, 2021
BACKGROUND The sodium/iodide symporter (NIS) mediates active iodide accumulation in the thyroid follicular cell. Autosomal recessive iodide transport defect (ITD)-causing loss-of-function NIS variants lead to dyshormonogenic congenital hypothyroidism due
Carlos Eduardo Bernal Barquero   +7 more
semanticscholar   +1 more source

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