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Development of antidotes for sodium monofluoroacetate (1080)
Biomarkers, 2001 Baits containing sodium monofluoroacetate (1080) are commonly used in New Zealand during feral pest control operations. However, each year, a number of domestic dogs are unintentionally killed during these control operations, and a suitable antidote to 1080 intoxication is required. The primary toxic mechanism of 1080 is well known.
C J, Cook +3 more
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Hemodynamic abnormalities in sodium monofluoroacetate intoxication
Human and Experimental Toxicology, 1999Hypotension is one of the most important predictors of mortality in sodium monofluoroacetate (SMFA) intoxication. This paper reports the hemodynamic response in one fatal and another survival case of SMFA intoxication. Despite correction of hypovolemia and with inotropic support, the patients remained in shock.
Chih-Hsien Chi +2 more
exaly +3 more sources
Determination of the sodium monofluoroacetate in serum by gas chromatography
Chromatographia, 2001 Sodium monofluoroacetate (NAFAc) has been widely used for vertebrate pest control, such as rabbits in Australia. However, NAFAc is extremely toxic to all vertebrates and its use is restricted. Although this compound is stringently restricted, the occurrence of accidental and homicidal poisoning is na ever-present possibility.
Demarchi, ACCO +3 more
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Persistence of sodium monofluoroacetate in rabbits and risk to non-target species
Human and Experimental Toxicology, 19951 Sodium monofluoroacetate (1080), a vertebrate pesti cide used in New Zealand, was administered orally to rabbits at two dose levels (sub-lethal and lethal) to determine how long 1080 would persist in plasma, liver, kidney, and muscle so that the risk of consump tion of meat from lethally or sub-lethally poisoned rab bits by non-target species could ...
S R, Gooneratne +4 more
exaly +3 more sources
Sodium monofluoroacetate (1080) risk assessment and risk communication
Toxicology, 2002Sodium monofluoroacetate (1080) is a vertebrate pesticide widely used for possum control in New Zealand. Fluoroacetate is also a toxic component of poisonous plants found in Australia, South Africa, South America, and India. Because of its importance and effectiveness in pest control and the highly toxic nature of this compound, its acute sub-lethal ...
Charles Eason
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Biodegradation of Sodium Monofluoroacetate (compound 1080) [PDF]
, 1979 The biological potential of some South Island soils for defluorination of sodium monofluoroacetate (NaFa) was examined. In these soils were found a diversity of bacteria: Pseudomonas sp., Bacillus subtilis, Aeromonas sp., Actinobacillus sp., Citrobacter sp., Staphylococcus aureus and Lactobacillus Spa Also found were the fungi: Acremonium strictum ...
Bong, Chui Lien
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Persistence of sodium monofluoroacetate (1080) in baits under simulated rainfall
New Zealand Journal of Agricultural Research, 1995Abstract The rate of leaching of sodium monofluoroacetate (1080) by simulated rainfall was determined for carrot and possum pellet baits containing 0.08 and 0.15% 1080. Carrot baits were highly water‐resistant and showed no decline in 1080 concentration after 200 mm of rain. It is therefore inadvisable to use carrot bait in arid areas
C T Eason
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Sodium monofluoroacetate (Compound 1080) poisoning in dogs
Australian Veterinary Journal, 2005Sodium monofluoroacetate (Compound 1080) is a widely used pesticide for control of feral animals such as the fox. Accidental poisoning of domestic animals occurs despite strict regulations on 1080 usage. Dogs are particularly susceptible to the toxin.The mechanism of 1080 toxicity, susceptibility of target and non‐target species, persistence of 1080 in
C S S, Goh +4 more
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Uptake and Persistence of Sodium Monofluoroacetate (1080) in Plants
Bulletin of Environmental Contamination and Toxicology, 1998In New Zealand, large-scale control of introduced possums ( Trichosurus vulpecula) and rabbits (Oryctolagus cuniculus) is based on aerial application of baits containing the toxin sodium monofluoroacetate (1080). The high solubility of 1080 has caused concerns about the environmental effects of 1080 leaching from baits into soil and waterways ...
S C, Ogilvie, L H, Booth, C T, Eason
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