Results 11 to 20 of about 1,118,668 (288)

Use of the optimized sodium thiosulfate regimen for the treatment of calciphylaxis in Chinese patients. [PDF]

Ren Fail, 2022
Background Sodium thiosulfate (STS) can be used to treat patients diagnosed with calciphylaxis, which is a rare life-threatening syndrome. However, our patients treated with the recommended STS regimen presented with serious adverse events, resulting in ...
Yang X, Liu Y, Xie X, Shi W, Si J, Li X, Zhang X, Liu B.   +7 more
europepmc   +4 more sources

Clinical Efficacy and Safety of Sodium Thiosulfate in the Treatment of Uremic Pruritus: A Meta-Analysis of Randomized Controlled Trials

Toxins, 2021
Uremic pruritus is a distressful complication of chronic kidney disease and results in impaired quality of life and higher mortality rates. Intravenous sodium thiosulfate has been reported to alleviate pruritus in hemodialysis patients.
Ping-Hsun Lu, Hui-En Chuo, Ko-Lin Kuo, Jian-Fu Liao, Po-Hsuan Lu   +4 more
doaj   +2 more sources

Success of small-dose fractionated sodium thiosulfate in the treatment of calciphylaxis in a peritoneal dialysis patient

BMC Nephrology, 2022
Background Calciphylaxis, or calcific uremic arteriolopathy (CUA), is a rare, fatal disorder of microvascular calcification and thrombosis that typically affects patients with end-stage renal disease (ESRD) receiving long-term dialysis.
Yuan Lu, Lei Shen, Ling Zhou, Deyu Xu
doaj   +2 more sources

Anti-proliferative potential of sodium thiosulfate against HT 29 human colon cancer cells with augmented effect in the presence of mitochondrial electron transport chain inhibitors

Asian Pacific Journal of Tropical Biomedicine, 2020
Objective: To compare the anti-proliferative effect of sodium thiosulfate on human colorectal cancer cells (HT-29) and normal small intestine cells (IEC6).
Bhavana Sivakumar, Sri Rahavi Boovarahan, Gino A Kurian   +2 more
doaj   +2 more sources

Safety and Tolerability of Sodium Thiosulfate in Patients with an Acute Coronary Syndrome Undergoing Coronary Angiography: A Dose-Escalation Safety Pilot Study (SAFE-ACS)

Journal of Interventional Cardiology, 2020
Background. In animal studies, hydrogen sulfide (H2S) has been shown to protect the heart from ischemia-reperfusion injury. This study evaluates the safety and tolerability of the H2S donor sodium thiosulfate (STS) in patients with acute coronary ...
Marie-Sophie L. Y. de Koning, Solmaz Assa, Carlijn G. Maagdenberg, Dirk J. van Veldhuisen, Andreas Pasch, Harry van Goor, Erik Lipsic, Pim van der Harst   +7 more
doaj   +2 more sources

Sodium Thiosulfate for Calciphylaxis Treatment in Patients on Peritoneal Dialysis: A Systematic Review. [PDF]

Medicina (Kaunas), 2023
Limited data are available on the utilization of sodium thiosulfate (STS) treatment for calciphylaxis in peritoneal dialysis (PD) patients, while it is well-studied in hemodialysis (HD) patients.
Gossett C, Suppadungsuk S, Krisanapan P, Tangpanithandee S, Thongprayoon C, Mao MA, Cheungpasitporn W.   +6 more
europepmc   +2 more sources

Biomimetic Grapefruit-Derived Extracellular Vesicles for Safe and Targeted Delivery of Sodium Thiosulfate against Vascular Calcification. [PDF]

ACS Nano, 2023
As the prevalence of vascular calcification (VC), a strong contributor to cardiovascular morbidity and mortality, continues to increase, the need for pharmacologic therapies becomes urgent.
Feng W, Teng Y, Zhong Q, Zhang Y, Zhang J, Zhao P, Chen G, Wang C, Liang XJ, Ou C.   +9 more
europepmc   +2 more sources

Protection by Means of Perinatal Oral Sodium Thiosulfate Administration against Offspring Hypertension in a Rat Model of Maternal Chronic Kidney Disease. [PDF]

Antioxidants (Basel), 2023
Tain YL, Hou CY, Chang-Chien GP, Lin S, Hsu CN.   +4 more
europepmc   +3 more sources

Rationally designed sodium thiosulfate-loaded solid lipid nanoparticles for inner ear delivery and prevention of medication-induced ototoxicity.

J Mater Chem B
Chakrabarty B, Thakur NS, Joshi AD, Agrahari V.   +3 more
europepmc   +3 more sources

Intraarterial Degradation of Calcium Hydroxylapatite Using Sodium Thiosulfate – An In Vitro and Cadaveric Study [PDF]

Aesthetic surgery journal, 2021
BACKGROUND The most severe complications following soft tissue filler injections result from the intraarterial administration of the filler product.
Mariya Yankova, Tatjana Pavicic, Konstantin Frank, Thilo L. Schenck, Kate Beleznay, Diana L. Gavril, Jeremy B. Green, Daria Voropai, Deanne Mraz Robinson, Sebastian Cotofana   +9 more
openalex   +2 more sources