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Report on Standardization of Sodium Thiosulfate Solutions
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Kinetics of sodium thiosulfate, a cisplatin neutralizer
Clinical Pharmacology and Therapeutics, 1984Sodium thiosulfate kinetics were studied in eight subjects, six of whom were given the drug as a cisplatin neutralizer. Thiosulfate at a dose of 12 gm/m2 was injected by continuous intravenous infusion over 6 hr. Under these conditions, steady-state plasma concentrations were not achieved and apparent volume of distribution could not be calculated. The
Stephen B. Howell+2 more
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Efficacy of sodium thiosulfate for the treatment for calciphylaxis
Clinical Nephrology, 2011Calciphylaxis is a rare condition with dismal prognosis that affects patients with ESRD. Sodium thiosulfate (STS) may play a therapeutic role but its proposed efficacy is based on case reports and thus subject to publication bias.We identified all patients who received STS for any indication over a 5-year period through pharmacy records of 4 hospitals,
Sharon M. Moe+4 more
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Intralesional Sodium Thiosulfate for the Treatment of Calciphylaxis
JAMA Dermatology, 2013Calciphylaxis is a potentially fatal disorder of abnormal calcium deposition. Patients commonly present with painful retiform to stellate purpuric lesions that often undergo ulceration and necrosis, increasing the risk of infection and life-threatening sepsis.
Gideon P. Smith+7 more
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Pilot testing of sodium thiosulfate
Environmental Progress, 1986AbstractPilot plant tests have been conducted to evaluate sodium thiosulfate as an oxidation inhibition additive in five lime/limestone slurry flue gas desulfurization processes. It was found that the oxidation rate of absorbed sulfur dioxide (SO2) was reduced by more than 50 percent in the presence of 100 to 200 ppm of thiosulfate ion in the scrubbing
John C. S. Chang, Theodore G. Brna
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SODIUM THIOSULFATE AND THE ELIMINATION OF ARSENIC
Journal of the American Medical Association, 1938The administration of sodium thiosulfate for the treatment of arsenical dermatitis has been an accepted procedure among dermatologists ever since it was first introduced by Ravaut, 1 in 1920. In this country McBride and Dennie 2 confirmed the value of the treatment, and since then numerous clinicians have attested its value in shortening the duration ...
Samuel Ayres, Nelson Paul Anderson
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Hydroxycobalamin/sodium thiosulfate as a cyanide antidote
The Journal of Emergency Medicine, 1987Severe, acute cyanide poisoning is uncommon and can be very difficult to diagnose if a history of exposure is unavailable. Victims of smoke inhalation may have significant cyanide poisoning as well as carbon monoxide toxicity. The Lilly Cyanide Antidote Kit currently available in America unfortunately has its own inherent toxicity.
Alan H. Hall, Barry H. Rumack
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Contact allergy to gold sodium thiosulfate
Contact Dermatitis, 1995278 consecutive patients with suspected contact dermatitis were patch tested with the European standard series and gold sodium thiosulfate (0.5% pet.): 13 patients (4.6%) had a positive allergic response to gold sodium thiosulfate (GST). All of these patients were female, with a mean age of 37 years.
D. Burrows+3 more
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