Results 51 to 60 of about 1,761,536 (299)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Powder metallurgical materials and processes for soft magnetic applications [PDF]

, 2018
For many designers of electrical machines, the term “soft magnetic materials” automatically means laminated electrical sheet. This is unfortunate, since for many applications, particularly at low frequencies, laminated sheet is rarely the best material ...
Dougan, Mark J.
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Light-induced pressurization effect in Au–Ni heterostructures for plasmonic photocatalysis

Nature Communications
Plasmonic photocatalysis offers a promising route to harvest solar energy and drive chemical reactions by the generated heat and energetic charge carriers towards a low-carbon economy. Understanding the mechanisms of plasmonic photocatalysis is vital for
Zhijie Zhu, Shuairen Qian, Xudong Dong, Shuang Liu, Yuxuan Zhou, Kaiqi Nie, Xingda An, Chaoran Li, Yi Cheng, Binhang Yan, Kai Feng, Xiaohong Zhang, Le He   +12 more
doaj   +1 more source

Efficient isogeometric thin shell formulations for soft biological materials

, 2017
This paper presents three different constitutive approaches to model thin rotation-free shells based on the Kirchhoff-Love hypothesis. One approach is based on numerical integration through the shell thickness while the other two approaches do not need ...
Roohbakhshan, Farshad, Sauer, Roger A.
core   +1 more source

Safety experiments for small robots investigating the potential of soft materials in mitigating the harm to the head due to impacts [PDF]

, 2019
There is a growing interest in social robots to be considered in the therapy of children with autism due to their effectiveness in improving the outcomes.
Alhaddad, Ahmad Yaser, Bonarini, Andrea, Cabibihan, John-John, Hayek, Ahmad   +3 more
core   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Reaction mechanism on Ni-C2-NS single-atom catalysis for the efficient CO2 reduction reaction

Journal of Experimental Nanoscience, 2021
Ni-based single-atom catalysis (Ni-SAC) has been experimentally reported with superior performance in reducing CO2 to CO. However, due to the ambiguities in its structures, the active sites of Ni-SAC that are responsible for superior performance have not
Qi Yuan, Youyong Li, Peiping Yu, Bingyun Ma, Liang Xu, Qintao Sun, Hao Yang, Miao Xie, Tao Cheng   +8 more
doaj   +1 more source

Fingerprinting Soft Materials: A Framework for Characterizing Nonlinear Viscoelasticity

, 2007
We introduce a comprehensive scheme to physically quantify both viscous and elastic rheological nonlinearities simultaneously, using an imposed large amplitude oscillatory shear (LAOS) strain.
A. E. Hosoi, Abramowitz M., Bird R., Debbaut B., Ferry J. D., Gareth H. McKinley, Kim H., Larson R. G., Pipe C. J., Randy H. Ewoldt   +9 more
core   +1 more source