Results 61 to 70 of about 1,761,536 (299)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Flexible Substrate-Compatible and Efficiency-Improved Quantum-Dot Light-Emitting Diodes with Reduced Annealing Temperature of NiO_x Hole-Injecting Layer

Molecules
The growing demand for wearable and attachable displays has sparked significant interest in flexible quantum-dot light-emitting diodes (QLEDs). However, the challenges of fabricating and operating QLEDs on flexible substrates persist due to the lack of ...
Shuai-Hao Xu, Jin-Zhe Xu, Ying-Bo Tang, Shu-Guang Meng, Wei-Zhi Liu, Dong-Ying Zhou, Liang-Sheng Liao   +6 more
doaj   +1 more source

Spontaneous liquid crystal and ferromagnetic ordering of colloidal magnetic nanoplates

Nature Communications, 2016
Ferromagnetism has been known as a material property of solids since the time of the ancient Greeks. Here, Shuai et al. report that magnetic nanoplates suspended in a simple solvent can spontaneously align to form a ferromagnetic liquid, capable of both ...
M. Shuai, A. Klittnick, Y. Shen, G. P. Smith, M. R. Tuchband, C. Zhu, R. G. Petschek, A. Mertelj, D. Lisjak, M. Čopič, J. E. Maclennan, M. A. Glaser, N. A. Clark   +12 more
doaj   +1 more source

A metal-free photocatalyst for highly efficient hydrogen peroxide photoproduction in real seawater

Nature Communications, 2021
It is a challenge to produce hydrogen peroxide in seawater by photocatalysis. Here, the authors design and synthesize a metal-free photocatalyst based on carbon dots with a salt-protective electron sink effect, which exhibits enhanced hydrogen peroxide ...
Qingyao Wu, Jingjing Cao, Xiao Wang, Yan Liu, Yajie Zhao, Hui Wang, Yang Liu, Hui Huang, Fan Liao, Mingwang Shao, Zhenghui Kang   +10 more
doaj   +1 more source

Slow dynamics, aging, and glassy rheology in soft and living matter

, 2006
We explore the origins of slow dynamics, aging and glassy rheology in soft and living matter. Non-diffusive slow dynamics and aging in materials characterised by crowding of the constituents can be explained in terms of structural rearrangement or ...
Alcaraz, Alsayed, Bandyopadhyay, Bandyopadhyay, Becu, Bellour, Bergenholtz, Berne, Berthier, Bonn, Bouchaud, Bouchaud, Bouchaud, Bouchaud, Bursac, Cates, Cates, Cates, Chung, Cipelletti, Cipelletti, Cipelletti, Cipelletti, Cloitre, Cloitre, Courtland, Dennis Liang, Desprat, Durian, Durian, Edwards, Evans, Fabry, Falus, Farr, Fielding, Gang, Götze, Head, Hébraud, Hébraud, James L. Harden, Ketz, Khan, Knaebel, Krall, Laudadio, Lenormand, Lequeux, Liu, Liu, Lumma, Mackley, Macosko, Majmudar, Mason, Mason, Mason, Mayer, Melrose, Monthus, Panizza, Pine, Ramos, Ranjini Bandyopadhyay, Richert, Richter, Robert L. Leheny, Schwarz, Segré, Sollich, Sollich, Struik, Sun, Tao, Trappe, Trappe, Tölle, van Megan, Van Megan, Weeks, Yardimci   +81 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A green approach to dual-drug nanoformulations with targeting and synergistic effects for cancer therapy

Drug Delivery, 2017
Exploration of efficient dual-drug nanohybrids, particularly those with high drug loading, specific targeting property, and long-termed stability, is of highly importance in cancer therapy.
Shichao Wu, Xiangrui Yang, Yue Lu, Zhongxiong Fan, Yang Li, Yuan Jiang, Zhenqing Hou   +6 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery

Nature Communications, 2022
Inflammatory bowel disease (IBD) is a complex disease that is associated with multiple genetic and environmental variables. Here the authors develop genetically engineered probiotics with selfproducing functional proteins and biofilm self-coating for ...
Jun Zhou, Maoyi Li, Qiufang Chen, Xinjie Li, Linfu Chen, Ziliang Dong, Wenjun Zhu, Yang Yang, Zhuang Liu, Qian Chen   +9 more
doaj   +1 more source

Stretchable elastic synaptic transistors for neurologically integrated soft engineering systems [PDF]

, 2019
Artificial synaptic devices that can be stretched similar to those appearing in soft-bodied animals, such as earthworms, could be seamlessly integrated onto soft machines toward enabled neurological functions.
Chai, Yang, Ershad, Faheem, Gao, Li, Gu, Guoying, Kim, Hae-Jin, Liu, Yanghui, Rao, Zhoulyu, Shim, Hyunseok, Sim, Kyoseung, Thukral, Anish, Wang, Xinran, Wang, Xu, Yang, Pinyi, Yu, Cunjiang   +13 more
core   +1 more source