Results 51 to 60 of about 1,449,895 (339)

Cooperation in a fluid swarm of fuel-free micro-swimmers

Nature Communications, 2022
The authors introduce a light powered artificial micro-swimmers performing biological-like dynamics relevant for swarm robotics. The experimental dense swarms are shown to form artificial active clusters with internal fluid-like and turbulent dynamics ...
Matan Yah Ben Zion, Yaelin Caba, Alvin Modin, Paul M. Chaikin   +3 more
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Emergent memory from tapping collisions in active granular matter

Communications Physics
In an equilibrium thermal environment, random elastic collisions between background particles and a tracer establish the picture of Brownian motion fulfilling the celebrated Einstein relation between diffusivity and mobility.
Lorenzo Caprini, Anton Ldov, Rahul Kumar Gupta, Hendrik Ellenberg, René Wittmann, Hartmut Löwen, Christian Scholz   +6 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Ferroelectric Nematic Liquid Crystals Showing High Birefringence

Advanced Science
High birefringence nematic liquid crystals are particularly demanded for adaptive optics applications in the infrared spectrum because it enable a thinner cell gap for achieving fast response time and improved diffraction efficiency.
Yaohao Song, Xiang Huang, Xinxin Zhang, Minghui Deng, Satoshi Aya, Mingjun Huang   +5 more
doaj   +1 more source

What is fluidity? Designing an experimental system to probe stress and velocity fluctuations in flowing suspensions

EPJ Web of Conferences, 2017
We develop a method to investigate the microscopic origin of granular fluidity. We design a Couette cell in which we can probe the flow of soft hydrogel suspensions.
Workamp Marcel, Alaie Sepideh, Dijksman Joshua A.   +2 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Transparent gel engineering materials for 3D gel printing

Nihon Kikai Gakkai ronbunshu, 2017
Recently our group developed 3D gel printer named “SWIM-ER” (soft and wet industrial material - easy realizer). Here we aim to improve the gel materials used for SWIM-ER system about the problems around free-shaping, transparency, and mechanical strength.
Taishi TASE, Takafumi OTA, Koji OKADA, Kyuichiro TAKAMATSU, Azusa SAITO, Masaru KAWAKAMI, Hidemitsu FURUKAWA   +6 more
doaj   +1 more source

Coarse-graining dynamics by telescoping down time-scales: comment for Faraday FD144 [PDF]

Faraday Discuss., 144, 323 (2010), 2010
I briefly review some concepts related to coarse-graining methods for the dynamics of soft matter systems and argue that such schemes will almost always need to telescope down the physical hierarchy of time-scales to a more compressed, but more computationally manageable, separation.
arxiv   +1 more source