Results 61 to 70 of about 1,449,895 (339)
Molecular Oncology, EarlyView.Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns +4 more
wiley +1 more source
Boost the Public Demand for Soft Matter Education and Career Opportunities with a Homemade Video [PDF]
arXiv, 2020 The study aims to promote the awareness and education of soft matter which has become a popular research topic owing to its capability of developing self-assembling materials for numerous industries such as self-healing materials. To pursue after this aim, we composed a homemade video to illustrate the soft matter concepts, followed by distributing a ...
arxiv
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
New insight into cataract formation -- enhanced stability through mutual attraction [PDF]
, 2007 Small-angle neutron scattering experiments and molecular dynamics simulations combined with an application of concepts from soft matter physics to complex protein mixtures provide new insight into the stability of eye lens protein mixtures.
A. Stradner +12 more
core +2 more sources
Sequential self-assembly of DNA functionalized droplets
Nature Communications, 2017 Natural complex systems are often constructed by sequential assembly but this is not readily available for synthetic systems. Here, the authors program the sequential self-assembly of DNA functionalized emulsions by altering the DNA grafted strands.
Yin Zhang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Shear banding, aging and noise dynamics in soft glassy materials [PDF]
Soft Matter, 2009, 2008 The `soft glassy rheology' (SGR) model gives an appealing account of the flow of nonergodic soft materials in terms of the local yield dynamics of mesoscopic elements. Newtonian, power-law, and yield-stress fluid regimes arise on varying a `noise temperature', x.
arxiv +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
The EDGES 21 cm Anomaly and Properties of Dark Matter
, 2018 The recently claimed anomaly in the measurement of the 21 cm hydrogen absorption signal by EDGES at $z\sim 17$, if cosmological, requires the existence of new physics.
Fraser, Sean +10 more
core +1 more source
Exactly solvable model for a velocity jump observed in crack propagation in viscoelastic solids
Scientific Reports, 2017 Needs to impart appropriate elasticity and high toughness to viscoelastic polymer materials are ubiquitous in industries such as concerning automobiles and medical devices.
Naoyuki Sakumichi, Ko Okumura
doaj +1 more source