Results 61 to 70 of about 202,793 (380)
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis [PDF]
, 2016 Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted ...
Boel, Annekatrien +12 more
core +2 more sources
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Autopsy and Case Reports, 2022 Pleomorphic hyalinizing angiectatic tumor (PHAT) of soft tissues is a rare, non-metastatic tumor of unknown etiology and uncertain behavior, which may recur locally.
Eveline Cristina da Silva +3 more
doaj
Odontogenic Myxoma Of The Maxilla: A Clinical Case Report And Review Of Literature [PDF]
, 2013 Odontogenic myxomas are rare benign mesenchymal tumours of head and neck with a potential for local infiltration and recurrence. They appear to originate from the dental papilla, follicle or periodontal ligament in mandible and less commonly the ...
Bhardwaj, Vikram +3 more
core +2 more sources
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Commentary on "a case of paratesticular leiomyosarcoma successfully treated with orchiectomy and chemotherapy" [PDF]
, 2015 We have read with great interest the article written by Ko and colleagues on a particularly rare type of malignant mesenchymal tumor that is paratesticular leiomyosarcoma and we did appreciate the argumentation on the utility of adjuvant chemotherapy as ...
Marchetti, Paolo +3 more
core +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Soft Tissue Myxoma - A Case Report
Journal of Indian Academy of Oral Medicine and Radiology, 2004 Myxoma of bone is a benign neoplasm commonly found in the maxillofacial region These myxomas of bone are considered by Stout as true neoplasms. Odontogenic or central myxomas are common as compared to soft tissue myxoma.
Sanjib Kumar Khataniar +1 more
doaj
Autonomous Soft Tissue Retraction Using Demonstration-Guided Reinforcement Learning [PDF]
arXiv, 2023 In the context of surgery, robots can provide substantial assistance by performing small, repetitive tasks such as suturing, needle exchange, and tissue retraction, thereby enabling surgeons to concentrate on more complex aspects of the procedure.
arxiv
Advanced Primary Lymphoma of Oral Cavity: Report of a Case [PDF]
, 2014 Usually the oral manifestations of NHL are secondary to a more widespread involvement throughout the body, however, it can rarely present as a primary lesion in the oral cavity, having 0.1% - 0.2% prevalence.
Alirezaei, S. +4 more
core