Results 61 to 70 of about 241,864 (311)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

An unusual variant of atrophic dermatofibrosarcoma protuberans [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Dermatofibrosarcoma protuberans is an uncommon neoplasm that is most often seen in young adults. The most common clinical presentation is the protruding form; however, other subtypes are known, such as the atrophic.
Simone Silva da Costa Aragão   +3 more
doaj   +1 more source

Use of novel serum markers in clinical follow-up of Sertoli-Leydig cell turnours [PDF]

open access: yes, 2007
Background: Sertoli-Leyclig cell tumours of the ovary account for only 0.2% of malignant ovarian tumours. Two-thirds of all patients become apparent due to the tumour's hormone production. Methods: A 41-year-old patient (gravida 4, para 4) presented with
Campisi P   +12 more
core   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Soft Tissue Myxoma - A Case Report

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2004
Myxoma of bone is a benign neoplasm commonly found in the maxillofacial region These myxomas of bone are considered by Stout as true neoplasms. Odontogenic or central myxomas are common as compared to soft tissue myxoma.
Sanjib Kumar Khataniar   +1 more
doaj  

Pleomorphic hyalinizing angiectatic tumor of the vulva: literature review based on a rare presentation

open access: yesAutopsy and Case Reports, 2022
Pleomorphic hyalinizing angiectatic tumor (PHAT) of soft tissues is a rare, non-metastatic tumor of unknown etiology and uncertain behavior, which may recur locally.
Eveline Cristina da Silva   +3 more
doaj  

Lipoleiomyoma of the Uterus [PDF]

open access: yes, 2005
Lipoleiomyomas are uncommon benign neoplasms of uterus consisting of variable portions of mature lipocytes and smooth muscle cells. These tumours generally occur in asymptomatic obese perimenopausal or menopausal women.
Alper, Murat   +4 more
core  

Delayed phlegmon with gallstone fragments masquerading as soft tissue sarcoma. [PDF]

open access: yes, 2016
Complications from lost gallstones after cholecystectomy are rare but varied from simple perihepatic abscess to empyema and expectoration of gallstones.
Bateni, Cyrus P   +3 more
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Pediatric Oral/Maxillofacial Soft Tissue Sarcomas: A Clinicopathologic Report of Four Cases

open access: yesCase Reports in Oncology, 2016
Pediatric soft tissue sarcomas of the oral/maxillofacial region are rare neoplasms that present significant difficulty with respect to treatment and local control measures.
Joel C. Thompson   +6 more
doaj   +1 more source

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