Results 101 to 110 of about 2,534,544 (260)

New therapies in soft tissue sarcoma

, 2010
Importance of the field: Soft tissue sarcomas are rare mesenchymal tumors accounting for < 1% of all adult neoplasia. In the last decade, locally advanced and metastatic soft tissue sarcoma have been managed only through surgery, radiotherapy and ...
Frezza AM, Santini D, Vincenzi B, Tonini G   +3 more
core   +1 more source

Ewing's Sarcoma in Adults: A Predictive Nomogram and Survival Analysis of a Cohort of 937 Patients

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Ewing sarcoma is a rare malignancy of bone and soft tissue that most commonly affects children, adolescents, and young adults. Although multimodal treatment has improved survival in localised disease, outcomes remain poorer in adults, particularly in those with metastatic disease, larger tumours, or anatomically complex primary ...
Jonathan Gibson, Ben Thompson, Katie Williams, Chuck Lam, Shashank Chapala, Morgan Jones, Rajesh Botchu   +6 more
wiley   +1 more source

Exosomal miR-20a-5p derived from cisplatin-resistant osteosarcoma cells promotes chemoresistance via Inhibition of ferroptosis through targeting RUNX3

Scientific Reports
Cisplatin resistance continues to pose a significant challenge in the treatment of osteosarcoma, markedly impairing clinical outcomes. Accumulating evidence indicates that exosomal microRNAs (miRNAs) facilitate intercellular communication and play a ...
Peng Zhang, Luyue Deng, Kai Chen, Wenli Ding, Xiaoying Niu, Wen Tian   +5 more
doaj   +1 more source

Review on Lymph Node Metastases, Sentinel Lymph Node Biopsy, and Lymphadenectomy in Sarcoma

Current Oncology
Soft tissue sarcomas (STS) originating from connective tissue rarely affect the lymph nodes. However, involvement of lymph nodes in STS is an important aspect of prognosis and treatment. Currently, there is no consensus on the diagnosis and management of
Paulina Chmiel, Maria Krotewicz, Anna Szumera-Ciećkiewicz, Ewa Bartnik, Anna M. Czarnecka, Piotr Rutkowski   +5 more
doaj   +1 more source

Cardiac dysfunction among soft tissue sarcoma patients in Denmark

, 2016
Sumitra Shantakumar,1 Morten Olsen,2 Thao T Vo,3 Mette Nørgaard,2 Lars Pedersen,21Worldwide Epidemiology Department, GlaxoSmithKline Pte Ltd, Singapore; 2Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; 3Worldwide ...
Pedersen L, Olsen M, Shantakumar S, Vo TT, Nørgaard M   +4 more
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Soft tissue tumors: Clear cell sarcoma [PDF]

, 2003
Review on Soft tissue tumors: Clear cell sarcoma, with data on clinics, and the genes ...
Poppe, B, Speleman, Franki, Dhaene, K, K Dhaene, Forsyth, Ramses, Poppe, Bruce, B Poppe, RG Forsyth, F Speleman, Speleman, F, Dhaene, Karl, Forsyth, RG   +11 more
core   +1 more source

Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma

, 2015
Rita De Sanctis,1 Andrea Marrari,1 Silvia Marchetti,1 Chiara Mussi,2 Luca Balzarini,3 Fabio Romano Lutman,3 Primo Daolio,4 Stefano Bastoni,4 Alexia Francesca Bertuzzi,1,5 Vittorio Quagliuolo,2 Armando Santoro1 1Department of Medical Oncology and ...
Quagliuolo V, De Sanctis R, Mussi C, Marrari A, Bastoni S, Daolio P, Balzarini L, Santoro A, Lutman FR, Bertuzzi AF, Marchetti S   +10 more
core  

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

Beyond recurrence — a 47-year journey of long-term survival in Ewing's sarcoma with late complications

Oncology in Clinical Practice
The prognosis for patients diagnosed with Ewing's sarcoma (EwS) substantially improved since the integration of chemotherapy (CHT) into treatment protocols in the early 1970s. In the preceding series, the 5-year overall survival rate was documented to be
Piotr Remiszewski, Maryna Rubach, Anna M. Czarnecka   +2 more
doaj   +1 more source

Spotlight on olaratumab in the treatment of soft-tissue sarcoma: design, development, and place in therapy

, 2017
Elizabeth J Davis,1 Rashmi Chugh2 1Department of Internal Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, 2Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann ...
Davis EJ, Chugh R
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