New cell lines expanding the diversity of Ewing sarcoma models
What's new? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff +13 more
wiley +1 more source
Correction: An analysis of the distribution of bone and soft tissue sarcoma diagnoses and their disparities in Southwest Germany: a multicenter approach. [PDF]
Calukovic B +14 more
europepmc +1 more source
Precision medicine in orthopaedics: A review of current technologies and future directions
Abstract Purpose To synthesise the paradigm shift towards precision medicine in orthopaedics, where individual anatomical, biomechanical, molecular and kinematic characteristics are integrated into clinical decision‐making. Unlike traditional approaches applying uniform protocols, this review outlines how precision orthopaedics aims to tailor surgical ...
Patrick Sadoghi +5 more
wiley +1 more source
Impact of SAMHD1 and phosphorylated ATM levels on the progression and prognosis of patients with soft tissue sarcoma. [PDF]
Kim YJ +7 more
europepmc +1 more source
Robotic Resection of Parapharyngeal Follicular Dendritic Cell Sarcoma With Castleman Disease
Parapharyngeal follicular dendritic cell sarcoma (FDCS) is rare and may occur with Castleman disease. We describe the successful transoral robotic resection of a parapharyngeal FDCS associated with Castleman disease, highlighting the role of the robotic approach in achieving tissue diagnosis and definitive treatment.
Lily Huang +3 more
wiley +1 more source
Increasing Awareness of Soft-Tissue Sarcoma: Podcast of a Patient-HCP Discussion. [PDF]
Faskin G, Hackett S.
europepmc +1 more source
Setup of the da Vinci SP system. (A) The SP port is positioned transorally with the robotic cart docked at the patient’s head. (B) Two or three instruments and a 3D endoscope are inserted via a single port. ABSTRACT Objectives To assess the clinical practicality, procedural characteristics, and short‐term recovery outcomes of single‐port transoral ...
Ting‐Shen Lin +5 more
wiley +1 more source
The prognostic role of tumor-associated macrophage and cancer-associated fibroblast interactions in soft tissue sarcoma microenvironments. [PDF]
Zhou J +6 more
europepmc +1 more source
Dynamic Gelatin Hydrogels Crosslinked by Dithiolane‐Norbornene Click Chemistry
Gelatin‐norbornene (GelNB) and poly(ethylene glycol)‐tetra‐lipoic acid (PEG4LA) are modularly photo‐crosslinked into gelatin‐based hydrogels with dynamically tunable mechanics for expansion and differentiation of induced pluripotent stem cells (iPSC). ABSTRACT Hydrogels prepared from gelatin are ideal for mimicking the extracellular matrix (ECM) owing ...
Favour O. Afolabi +2 more
wiley +1 more source
The International Soft Tissue Sarcoma Consortium: The baseline analysis of rhabdomyosarcoma data. [PDF]
Bisogno G +15 more
europepmc +1 more source

