Results 31 to 40 of about 86,698,415 (262)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

A software service supporting software quality forecasting [PDF]

, 2019
Software repositories such as source control, defect tracking systems and project management tools, are used to support the progress of software projects.
Ayala Martínez, Claudia Patricia, Gómez Seoane, Cristina, Manzano Aguilar, Martí, López Cuesta, Lidia   +3 more
core   +1 more source

Software Sustainability in the Age of Everything as a Service [PDF]

, 2021
The need for acknowledging and managing sustainability as an essential quality of software systems has been steadily increasing over the past few years, in part as a reaction to the implications of ``software eating the world''. Especially the widespread
Lago, Patricia, Andrikopoulos, Vasilios; id_orcid, Andrikopoulos, Vasilios, Patricia Lago, Lago, Patricia,, Lago, Patricia; id_orcid, Andrikopoulos, Vasilios,, Vasilios Andrikopoulos   +7 more
core   +1 more source

An Implementation of Open Source-Based Software as a Service (SaaS) to Produce TOA and TOC Reflectance of High-Resolution KOMPSAT-3/3A Satellite Image

Remote Sensing, 2021
The majority of cloud applications are created or delivered to provide users with access to system resources or prebuilt processing algorithms for efficient data storage, management, and production.
Kwangseob Kim, Kiwon Lee
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Pattern-based software architecture for service-oriented software systems [PDF]

, 2010
Service-oriented architecture is a recent conceptual framework for service-oriented software platforms. Architectures are of great importance for the evolution of software systems.
Pahl, Claus, Barrett, Ronan
core  

Exploring the Key Risk Factors for Application of Cloud Computing in Auditing

Entropy, 2016
In the cloud computing information technology environment, cloud computing has some advantages such as lower cost, immediate access to hardware resources, lower IT barriers to innovation, higher scalability, etc., but for the financial audit information ...
Kuang-Hua Hu, Fu-Hsiang Chen, Wei-Jhou We   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Evaluating the Impact of Cloud Computing on SME Performance: A Systematic Review

Businesses
Small and medium-sized enterprises (SMEs) face substantial barriers in accessing reliable and cost-effective IT infrastructure, primarily due to economic constraints and limited technical resources.
Ayaphila Mkhize, Katleho D. Mokhothu, Mukhodeni Tshikhotho, Bonginkosi A. Thango   +3 more
doaj   +1 more source