Results 91 to 100 of about 11,364,785 (284)
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Software Defined User Centric 5G Wireless Network Framework
Dianxin kexue, 2015 The radio access network of 5G is a complex heterogeneous network.The independence of different protocols limits the network performance. To unify the management of the heterogeneous network and provide personalized service，a software defined user ...
Hua Qu +4 more
doaj +2 more sources
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
AutoSecSDNDemo: Demonstration of automated end-to-end security in software-defined networks
, 2016 S.347-348The complexity of modern communication networks and innovative cyber-attacking methods make it difficult to automatically detect and prevent attacks. Software-Defined Networking (SDN) separates the forwarding of network traffic from the decision
Nils Gruschka +9 more
core +1 more source
Software defined airborne tactical network for aeronautic swarm
Tongxin xuebao, 2017 Aeronautic swarm was a new kind of aeronautic operationa1 system inspired by bio1ogica1 swarm behaviors.Whi1e 1eading to a new usage way of future aeronautic operationa1 resources，aeronautic swarm wou1d bring new cha11enges to the airborne tactica1 ...
Shang-hong ZHAO +4 more
doaj +2 more sources
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Controller placement with critical switch aware in software-defined network (CPCSA). [PDF]
PeerJ Comput Sci, 2023 Muhammed Yusuf N +4 more
europepmc +1 more source