Results 51 to 60 of about 2,114,299 (265)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
, 2015 The proliferation of highly capable mobile devices such as smartphones and tablets has significantly increased the demand for wireless access. Software defined network (SDN) at edge is viewed as one promising technology to simplify the traffic offloading
Gu, Yunan +5 more
core +1 more source
The Role of Inter-Controller Traffic for Placement of Distributed SDN Controllers [PDF]
, 2016 We consider a distributed Software Defined Networking (SDN) architecture adopting a cluster of multiple controllers to improve network performance and reliability.
Bianco, Andrea +3 more
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
SDN-based virtual machine management for cloud data centers [PDF]
, 2014 Software-Defined Networking (SDN) is an emerging paradigm to logically centralize the network control plane and automate the configuration of individual network elements.
Cziva, Richard +3 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
A characterisation of reliability tools for Software Defined Networks [PDF]
, 2017 Software Defined Network (SDN) is a new paradigm in networking that introduces great flexibility, allowing the dynamic configuration of parts of the network through centralised programming.
Gallardo, María del Mar +3 more
core
Transiently Consistent SDN Updates: Being Greedy is Hard
, 2016 The software-defined networking paradigm introduces interesting opportunities to operate networks in a more flexible, optimized, yet formally verifiable manner. Despite the logically centralized control, however, a Software-Defined Network (SDN) is still
Amiri, Saeed Akhoondian +3 more
core +1 more source
Multi-domain service orchestration over networks and clouds: a unified approach [PDF]
, 2015 End-to-end service delivery often includes transparently inserted Network Functions (NFs) in the path. Flexible service chaining will require dynamic instantiation of both NFs and traffic forwarding overlays.
Czentye, J +7 more
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source