Results 251 to 260 of about 12,191,945 (322)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

An open-source replication for fast and accessible light propagation modeling in brain tissue. [PDF]

PLoS One
Berling D, Střeleček J, Iser T, Antolík J.   +3 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

An open-source software for building and simulating ordinary differential equation models in biology. [PDF]

PLoS One
Dos Santos BLM, Castro DAS, da Paz SFC, Pinheiro DJC, de Melo Quintela B, Lobosco M, Pigozzo AB.   +6 more
europepmc   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

The feasibility of using electrical impedance tomography to guide positive pressure airway clearance in children with cystic fibrosis and tracheobronchomalacia. [PDF]

Can J Respir Ther
Depiazzi J, Bourke C, Withers A.
europepmc   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

An open source platform to automate the design, verification, and manufacture of 3D printed microfluidic devices. [PDF]

Sci Rep
Goenner B, Temple S, Zapata S, Wakeham D, Snelgrove A, Gaillardon PE, Nordin GP, Gale BK.   +7 more
europepmc   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Cardiovascular disease in North African women: insights from the Middle East African Women CardioVascular Disease (MEA-WCVD) registry. [PDF]

Front Cardiovasc Med
Charfeddine S, Abid L, Chenik S, Ben Krayen I, Haddar O, Ghrab A, Boudiche S, Touati H, Ayedi O, Ammar MA, Ben Halima M, Ben Ayed H, Brahim A, ElAyech F, Allouche E, Thabet H, Mahfoudhi H, Jabloun TY, Ayadi Y, Ayadi A, Romdhani G, Gargouri H, Zidi O, Guedri MA, Tlili R, Trabelsi B, Hammami S, Othmen R, Antit S, Saidane S, Dardour S, Iddir S, Kharrat E, Cheikhrouhou A, Derwich M, Mrabet A, Lassoued T, Rekik E, Gmiha S, Laribi N, Lamine H, Triki Z, Ayari S, Boujelbene F, Boughzela E, Rekik H, Ben Ameur I, Abid S, Oueghlani K, Haggui A, Ben Halima A, Ouechtati W, Bennour E, Hammami R, Jabeur M, Zairi I, Drissa M, Addad F, Milouchi S, Mourali MS, Ben Slima H, Bezdah L, Neffati E, Ben Ameur Y, Kraiem S, Kachboura S, Kammoun I, Zakhama L, Lbn Hadj Amor H, Ben Hamda K, Messoudi Y, Ben Hlima N, Dahmani R, Gamra H, Ibn Elhadj Z, Denguir H, Ghorbel C, Mechri N, Ernez Hajri S, Mebazaa A, Ben Dhaou F, Trigui M, Fehri W, Abdessalem S.   +83 more
europepmc   +1 more source