High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson+5 more
wiley +1 more source
Quantitative perfusion cardiac magnetic resonance imaging: same same but different. [PDF]
Hoek R+6 more
europepmc +1 more source
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh+2 more
wiley +1 more source
Vira Workspace: A Novel Online Object-Oriented Framework as a SaaS for the Modeling and Simulation of Petrochemical Plant Networks. [PDF]
Fakhroleslam M.
europepmc +1 more source
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley +1 more source
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley +1 more source
Correction for '<i>Superior vena cava isolation added to pulmonary vein isolation enhances outcomes in paroxysmal atrial fibrillation: a meta-analysis with trial sequential analysis'</i>. [PDF]
europepmc +1 more source
Current Trends and Future Directions of Digital Pathology and Artificial Intelligence in Dermatopathology: A Scientometric-Based Review. [PDF]
Cocuz IG+9 more
europepmc +1 more source
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto+5 more
wiley +1 more source
Evaluation of AI Performance in Spinal Radiographic Measurements Compared to Radiologists: A Study of Accuracy and Efficiency. [PDF]
Pucciarelli F+13 more
europepmc +1 more source