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SOFTWARE: FROM PRODUCT TO SERVICE THE EVOLUTION OF A MODEL [PDF]

Among the consequences of the Enterprise 2.0 family technologies’ growingpopularity, we can observe the rise of a set of new business models for the use and employment ofsoftware applications, some of them also applicable for infrastructure components ...
Dragos Marian Mangiuc
core

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source

Computational mechanics software as a service project

Journal of Computer Science and Technology, 2018
Cloud computing promises great opportunities for the execution of scienti c and engineering applications. However, the execution of such kind of applications over Cloud infrastructures requires the accomplishment of many complex processes.
Carlos García Garino +4 more
doaj

Software as a Service und Datenschutz

, 2016
Die UB Mannheim geht als erste deutsche Universitätsbibliothek mit der Bibliothekssoftware Alma live, die von Ex Libris als Software as a Service konzipiert wurde. Diese Betriebsform bringt eine Reihe von datenschutzrechtlichen Herausforderungen mit sich, die die UB Mannheim erfolgreich gelöst hat. Die Universität Mannheim wurde von ZENDAS beraten, die
Francken-Welz, Marion von, Hänger, Christian +1 more
openaire +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou +12 more
wiley +1 more source

Data-Driven Decision Support in SaaS Cloud-Based Service Models

Applied Sciences
Software as a service (SaaS) is a major service model for delivering software to end users through the cloud. SaaS platforms provide their users with cost-efficient, flexible and scalable services that can be available on demand, anytime, and anywhere ...
Gerasimos Charizanis +4 more
doaj +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih +40 more
wiley +1 more source

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