Results 251 to 260 of about 122,840 (334)

FGDM: Reasoning Aware Multi-Agentic Framework for Software Bug Detection using Chain of Thought and Tree of Thought Prompting

open access: green
Srita Padmanabhuni   +4 more
openalex   +1 more source

Genetic prediction of blood cell reactivity and its potential causal influence on bone continuity and density disorders

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng   +8 more
wiley   +1 more source

Association between Plasma P‐tau217 and Alzheimer's Copathology and Cognitive Decline in Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective Clinically relevant Alzheimer's disease co‐pathology is common in Lewy body disorders. Plasma P‐tau217 is a sensitive biomarker for amyloid and tau pathology in Alzheimer's disease. The objective was to determine if plasma P‐tau217 associates with Alzheimer's disease co‐pathology and cognition in Lewy body disorders. Methods Participants had (
Thomas F. Tropea   +20 more
wiley   +1 more source

Photolyzable Polymer Brushes: Subtractive 3D Structuring of Surfaces Using Water and Light

open access: yesAngewandte Chemie, EarlyView.
Facile structuring of polymer brushes is achieved by flipping the process from controlled growth to controlled brush photolysis. Using surface‐initiated radical ring‐opening polymerization of cyclic monomers with photocleavable cyclobutane rings, photodegradable targets are embedded into the polymer chains. The enabled continuous subtractive patterning
Henrik Kalmer   +11 more
wiley   +2 more sources

Predominance of Ferroptotic Cell Death Mechanisms in Substantia Nigra Neurodegeneration in Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective The extent of neuronal loss in Parkinson's disease (PD) and the pathogenic processes underlying neuronal dysfunction and loss remain poorly understood. Here, we analyzed the expression of key molecules representing different cell death signaling pathways and their association with Lewy pathology, dopaminergic (DA) neuron loss and stage of PD ...
Yue Jing Heng   +3 more
wiley   +1 more source

Chromosome-scale genome assembly of the bed bug Cimex lectularius sheds light on a key insecticide resistance locus. [PDF]

open access: yesG3 (Bethesda)
Haberkorn C   +9 more
europepmc   +1 more source

Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective Accurate electrode placement and individual stimulation parameters influence the outcomes of subthalamic deep brain stimulation in Parkinson's disease. Neuroimaging‐based models can help evaluate how electrode placement impacts improvement, aiming to reduce the burden of programming.
Patricia Zvarova   +27 more
wiley   +1 more source

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