Results 21 to 30 of about 630,059 (264)

Integrating Multiple Interaction Networks for Gene Function Inference

Molecules, 2018
In the past few decades, the number and variety of genomic and proteomic data available have increased dramatically. Molecular or functional interaction networks are usually constructed according to high-throughput data and the topological structure of ...
Jingpu Zhang, Lei Deng
doaj   +1 more source

In silico drug repositioning based on the integration of chemical, genomic and pharmacological spaces

BMC Bioinformatics, 2021
Background Drug repositioning refers to the identification of new indications for existing drugs. Drug-based inference methods for drug repositioning apply some unique features of drugs for new indication prediction. Complementary information is provided
Hailin Chen, Zuping Zhang, Jingpu Zhang
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A Localized Collocation Solver Based on T-Complete Functions for Anti-Plane Transverse Elastic Wave Propagation Analysis in 2D Phononic Crystals

Mathematical and Computational Applications, 2020
In this paper, we introduce a novel localized collocation solver for two-dimensional (2D) phononic crystal analysis. In the proposed collocation solver, the displacement at each node is expressed as a linear combination of T-complete functions in each ...
Zhuo-Jia Fu, Lu-Feng Li, De-Shun Yin, Li-Li Yuan   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A short text entity disambiguation method based on BERT model and shortest path algorithm

Scientific Reports
Entity disambiguation is an important task in natural language processing that addresses situations where entity names mentioned in text may correspond to multiple real-world entities, with the goal of disambiguation by mapping entity names mentioned in ...
Xiaodong Liu, Dong Zhang, Tianhai Xiao, Sijing Mou, Junlin Du, Ran Zhao, Weihua Li, Wenjun Liu, Yaru Zhan   +8 more
doaj   +1 more source

KASS v.2.2. scheduling software for construction

MATEC Web of Conferences, 2016
The paper presents fourth version of specialist useful software in scheduling KASS v.2.2 (Algorithm Scheduling Krzeminski System). KASS software is designed for construction scheduling, specially form flow shop models.
Krzemiński Michał
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Expression and Analysis of Uncertainty in Deep Foundation Pit Design Scheme Decision-Making

Advances in Civil Engineering
The burgeoning urbanization of major cities has precipitated a critical examination of deep foundation pit projects, with escalating costs, protracted construction phases, complex site conditions, and specialized technical requirements.
Yu Cui, Qun Wang, Tiebing Chen, Ronghui Deng, Xiaoliang Chen   +4 more
doaj   +1 more source

YOLOv7-Branch: A Jujube Leaf Branch Detection Model for Agricultural Robot

Sensors
The intelligent harvesting technology for jujube leaf branches presents a novel avenue for enhancing both the quantity and quality of jujube leaf tea, whereas the precise detection technology for jujube leaf branches emerges as a pivotal factor ...
Ruijun Jing, Jijiang Xu, Jingkai Liu, Xiongwei He, Zhiguo Zhao   +4 more
doaj   +1 more source