Results 71 to 80 of about 630,059 (264)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Software Construction by Stepwise Feature Introduction [PDF]
, 2002 We study a method for software construction that is based on introducing new features to an evolving system one by one. A layered software architecture is proposed to support this method. We show how to describe the software with UML diagrams. We provide an exact semantics for the UML diagrams employed in the software architecture, using refinement ...
openaire +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
البرمجيات الحـــــديثة في المســــــــــح الكــــــمي للمشــــــــــــاريع الإنشــــــــــــــائية
Journal of Engineering and Sustainable Development, 2014 The engineering project management is one of the most important elements contributing to the success or failure of a business, there is no doubt about how important is the management to succeed in any area, especially in the field of construction ...
محمد مصــلح سلــمان +1 more
doaj
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
SOFTWARE OF AUTOMATION CONSTRUCTION FOR DISTANCE COURSE
Інформаційні технології і засоби навчання, 2010 Actual problems of distance courses authers automation work are considered. The system which can be co-ordinated with international standard SCORM or with a platform of distance learning is offered.
Yuriy M. Bogachkov, Pavlo S. Ukhan
doaj
Advances in Mechanical Engineering, 2016 Numerous infrastructures, especially the bridge, require some safe inspection and assessment at the soonest when hit by a disaster like catastrophic earthquake.
Xuefeng Zhao +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source