Results 111 to 120 of about 175,129 (304)

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey   +8 more
wiley   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer   +4 more
wiley   +1 more source

A model for software development cost estimation with system dynamic approach

open access: yesIranian Journal of Information Processing & Management, 2019
Software development is a complex and intricate process due to the number of factors involved, such as human factors, the complexity of developing products, the diversity of development levels, and the management problems of large projects.
Mahbubeh Rivadeh, Ameneh Khadivar
doaj  

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

An Investigation into Software Estimation Methods

open access: yes
There are currently no fully validated estimation approaches that can accurately predict the effort needed for developing a software system (Kitchenham, et al, 1995).
Hamdan, Khaled
core  

Physician‐Scientist Pipeline for Pediatric Rheumatology: The Current Landscape and Future Perspectives

open access: yesArthritis Care &Research, EarlyView.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu   +2 more
wiley   +1 more source

The use of simulation techniques for hybrid software cost estimation and risk analysis

open access: yes, 2022
S.115-174Cost estimation is a crucial field for companies developing software or software-intensive systems. Besides point estimates, effective project management also requires information about cost-related project risks, e.g., a probability ...
Ishigai, Yasushi   +5 more
core  

Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai   +7 more
wiley   +1 more source

Research on Application Technology for Software Cost Estimation Models

open access: yes, 2006
软件成本估算模型的目的在于帮助人们更好的理解软件项目的成本问题,进行准确的估算。因而,软件成本估算模型的广泛应用,一方面有助于软件采购方与开发者更好的理解软件成本,获得更准确的估算;另一方面可以发现现有模型的不足,为模型改进提供依据。然而,现有的软件成本估算模型,由于缺少相应应用技术的支持,并没有得到足够广泛的应用。软件采购方与开发者仍然饱受软件成本问题的困扰。因而,软件成本估算模型应用技术是值得研究的重要问题。 软件成本估算模型的良好应用需要三方面:1)有效的估算模型,即正确使用的前提下 ...
袁荣
core  

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