Results 81 to 90 of about 7,545,585 (279)

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

An Intelligent Recommender and Decision Support System (IRDSS) for Effective Management of Software Projects

open access: yesIEEE Access, 2020
The management and estimation of agile projects are challenging tasks for software companies due to their high failure rates. This paper emphasizes how to improve management and estimation challenges in the context of scrum, which is an agile process ...
Muhammad Hamid   +7 more
doaj   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph   +5 more
wiley   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Software cost estimation with fuzzy inputs: Fuzzy modelling and aggregation of cost drivers [PDF]

open access: yes, 2005
summary:Parametric software cost estimation models are well-known and widely used estimation tools, and several fuzzy extensions have been proposed to introduce a explicit handling of imprecision and uncertainty as part of them.
Crespo, Javier   +3 more
core   +1 more source

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey   +8 more
wiley   +1 more source

Software Cost Estimation using Function Point with Non Algorithmic Approach [PDF]

open access: yes, 2013
Cost estimation is one of the most challenging tasks in project management. It is to accurately estimate needed resources and required schedules for software development projects.
Dr. N. Balaji   +2 more
core  

Software cost estimation, benchmarking, and risk assessment

open access: yes, 2022
- Both the CoBRA method and its presentation are driven by and aimed at industrial practice - A complete and comprehensible specification of all relevant CoBRA processes is presented - The methodological concepts and their usage are illustrated by ...
Trendowicz, Adam
core   +1 more source

Dimensionality reduction and machine learning based model of software cost estimation

open access: yesFrontiers in Physics
Software Cost Estimation (SCE) is one of the research priorities and challenges in the construction of cyber-physical-social systems (CPSSs). In CPSS, it is urge to process environmental and social information accurately and use it to guide social ...
Wei Zhang   +7 more
doaj   +1 more source

A Size Estimation Model for Board-Based Desktop Games

open access: yesIEEE Access, 2017
Software size estimation plays a key role in the planning of projects at the time of project inception. This paper describes the derivation, validation, and usage of a parametric model meant for estimating the size of board-based desktop games.
Nosheen Sabahat   +2 more
doaj   +1 more source

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