Results 51 to 60 of about 366,797 (298)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Software defined networking firewall for industry 4.0 manufacturing systems

Journal of Industrial Engineering and Management, 2018
Purpose: In order to leverage automation control data, Industry 4.0 manufacturing systems require industrial devices to be connected to the network.
Akihiro Tsuchiya, Francisco Fraile, Ichiro Koshijima, Angel Ortiz, Raul Poler   +4 more
doaj   +1 more source

Design Concept for a Failover Mechanism in Distributed SDN Controllers [PDF]

, 2017
Software defined networking allows the separation of the control plane and data plane in networking. It provides scalability, programmability, and centralized control. It will use these traits to reach ubiquitous connectivity.
Kong, Nathan
core   +2 more sources

Performance modelling and analysis of software defined networking [PDF]

, 2016
Software Defined Networking (SDN) is an emerging architecture for the next-generation Internet, providing unprecedented network programmability to handle the explosive growth of Big Data driven by the popularisation of smart mobile devices and the ...
Hu, JH, Miao, WM, Min, GM, Wang, HW, Wu, Y   +4 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

FCR: Fast and Consistent Controller-Replication in Software Defined Networking

IEEE Access, 2019
We consider the problem of coordination among replicated SDN controllers, where the challenge is to ensure a consistent view of the network while reacting to network events in a prompt manner.
Maaz Mohiuddin, Mia Primorac, Eleni Stai, Jean-Yves Le Boudec   +3 more
doaj   +1 more source

Wireless Mesh Software Defined Networks (wmSDN) [PDF]

2013 IEEE 9th International Conference on Wireless and Mobile Computing, Networking and Communications (WiMob), 2013
In this paper we propose to integrate Software Defined Networking (SDN) principles in Wireless Mesh Networks (WMN) formed by OpenFlow switches. The use of a centralized network controller and the ability to setup arbitrary paths for data flows make SDN a handy tool to deploy fine-grained traffic engineering algorithms in WMNs.
DETTI, ANDREA, Pisa, C, SALSANO, STEFANO DOMENICO, BLEFARI MELAZZI, NICOLA   +3 more
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Benefits, Security and Issues in Software Defined Networking (SDN)

NUST Journal of Engineering Sciences, 2016
Applications used now a day are bandwidth hungry like Online Shopping, IPTV, E-Commerce and many other which require more and more bandwidth as well as continuous bandwidth.
Nasir Shahzad, Ghulam Mujtaba, Manzoor Elahi   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source