Results 51 to 60 of about 5,927,341 (295)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Future Scenarios for Software-Defined Metro and Access Networks and Software-Defined Photonics

open access: yesPhotonics, 2017
In recent years, architectures, devices, and components in telecommunication networks have been challenged by evolutionary and revolutionary factors which are drastically changing the traffic features.
Tommaso Muciaccia   +1 more
doaj   +1 more source

Software defined cognitive networking: supporting intelligent online video streaming

open access: yes, 2018
Adaptive media such as HTTP adaptive streaming (HAS) is becoming a standard tool for online video distribution. The non-cooperative competition of network resources between a growing number of adaptive video applications has a significant detrimental ...
Mu Mu, Mu, Mu
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Benefits, Security and Issues in Software Defined Networking (SDN)

open access: yesNUST Journal of Engineering Sciences, 2016
Applications used now a day are bandwidth hungry like Online Shopping, IPTV, E-Commerce and many other which require more and more bandwidth as well as continuous bandwidth.
Nasir Shahzad   +2 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Software defined networking firewall for industry 4.0 manufacturing systems

open access: yesJournal of Industrial Engineering and Management, 2018
Purpose: In order to leverage automation control data, Industry 4.0 manufacturing systems require industrial devices to be connected to the network.
Akihiro Tsuchiya   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

FCR: Fast and Consistent Controller-Replication in Software Defined Networking

open access: yesIEEE Access, 2019
We consider the problem of coordination among replicated SDN controllers, where the challenge is to ensure a consistent view of the network while reacting to network events in a prompt manner.
Maaz Mohiuddin   +3 more
doaj   +1 more source

Monitoring Jitter in Software Defined Networks

open access: yes, 2022
End-to-end jitter of a flow is an important metric that indicates the Quality of Service a user is experiencing, particularly for real-time applications such as video streaming, cloud gaming, and so on. Monitoring the jitter can help controllers make routing decisions for certain flows.
Jithin Kallukalam Sojan   +1 more
openaire   +3 more sources

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