Results 181 to 190 of about 21,707,590 (377)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Multidisciplinary Software Design for the Routine Monitoring and Assessment of Pain in Palliative Care Services: The Development of PainCheck. [PDF]

JCO Clin Cancer Inform, 2019
Allsop MJ, Johnson O, Taylor S, Hackett J, Allen P, Bennett MI, Bewick BM.   +6 more
europepmc   +1 more source

DESIGN AND ANALYSIS OF G10 GRAND AVENUE RESIDENCY BUILDING BY USING ETABS SOFTWARE [PDF]

M. Sathyavathi, D. Praveen Kumar, N. Dimple, CH. Sridhar, J. Kotesh Kumar   +4 more
openalex   +1 more source

ANALYSIS AND DESIGN OF STEEL BEAM USING ANSYS SOFTWARE

, 2023
Vijaysingh Katroliya, Er Mithilesh Kapse, Snehal Abhyankar, S Lau, G Hancock, L Sheah, P Khong, Young Kwon, Gregory Hancock, M Kikidis, C Papadopoulos, G Hancock, K Shivkuumaran, Nabil Abdel-Raheman, B Gotluru, B Schafer, T Pekoz, Wilson Reyes, Andres Guzman   +18 more
openalex   +1 more source

OctoUML: An Environment for Exploratory and Collaborative Software Design

2017 IEEE/ACM 39th International Conference on Software Engineering Companion (ICSE-C), 2017
B. Vesin, Rodi Jolak, M. Chaudron
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Automating risk analysis of software design models. [PDF]

ScientificWorldJournal, 2014
Frydman M, Ruiz G, Heymann E, César E, Miller BP.   +4 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Using Natural Language Prompts With AI Models for Low-Cost Assistive Software Design: Exploratory Comparative Evaluation. [PDF]

JMIR Rehabil Assist Technol
Bañuls-Lapuerta FA, Marti-Miralles V, Gónzalez-García RJ, Martínez-Rico G.   +3 more
europepmc   +1 more source

The effect of electronic health record software design on resident documentation and compliance with evidence-based medicine. [PDF]

PLoS One, 2017
Rodriguez Torres Y, Huang J, Mihlstin M, Juzych MS, Kromrei H, Hwang FS.   +5 more
europepmc   +1 more source