Results 181 to 190 of about 2,895,022 (317)

Improving the Design and Implementation of Software Systems uses Aspect Oriented Programming [PDF]

A design pattern is used as a static reusable component of object oriented design in the many patterns catalogue. The regular design pattern does not show any collaboration of shared resource between patterns in the software design. But generative design
Ghareb, Mazen, Allen, Gary, g.allen@hud.ac.uk   +2 more
core  

Clinical data integration and processing challenges in healthcare caused by contemporary software design. [PDF]

Digit Health
Petri V, Antoine T, Emma B, Hervé H, Emma F, Hana V.   +5 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Software Design Challenges in Time Series Prediction Systems Using Parallel Implementation of Artificial Neural Networks. [PDF]

ScientificWorldJournal, 2016
Manikandan N, Subha S.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Spectrum analysis on quality requirements consideration in software design documents. [PDF]

Springerplus, 2013
Kaiya H, Umemura M, Ogata S, Kaijiri K.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Dynamic software design for clinical exome and genome analyses: insights from bioinformaticians, clinical geneticists, and genetic counselors. [PDF]

J Am Med Inform Assoc, 2016
Shyr C, Kushniruk A, van Karnebeek CD, Wasserman WW.   +3 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Demonstration of a software design and statistical analysis methodology with application to patient outcomes data sets. [PDF]

Med Phys, 2013
Mayo C, Conners S, Warren C, Miller R, Court L, Popple R.   +5 more
europepmc   +1 more source