Results 141 to 150 of about 7,103,185 (329)

Lean Accounting Comes to Lean Software Development

, 2017
Thomas W. Stone
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

A cost effective communication model for requirements elicitation in global software development. [PDF]

Sci Rep, 2023
Rauf MA, Bibi S, Ali S, AlSaedi T, Ur Rehman S, Mahmood K, Kundi M.   +6 more
europepmc   +1 more source

EVALUATING FACTORS THAT CHALLENGE GLOBAL SOFTWARE DEVELOPMENT

, 2008
Gabriela N. Aranda, Aurora Vizcaíno, Alejandra Cechich, Mario Piattini   +3 more
openalex   +1 more source

Combining Agile with Traditional V Model for Enhancement of Maturity in Software Development [PDF]

, 2017
Ahmed Mateen, Madiha Tabassum, Akmal Rehan   +2 more
openalex   +1 more source

Laser transit anemometer software development program [PDF]

Algorithms were developed for the extraction of two components of mean velocity, standard deviation, and the associated correlation coefficient from laser transit anemometry (LTA) data ensembles. The solution method is based on an assumed two-dimensional
Abbiss, John B.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Prioritizing tasks in software development: A systematic literature review. [PDF]

PLoS One, 2023
Bugayenko Y, Bakare A, Cheverda A, Farina M, Kruglov A, Plaksin Y, Pedrycz W, Succi G.   +7 more
europepmc   +1 more source

For the Development of Application Software in Macromolecular Science

, 1999
Noritake Yasuoka
openalex   +2 more sources