Results 171 to 180 of about 7,204,729 (322)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Vibe coding: a new paradigm for biomedical software development. [PDF]

BioData Min
Moore JH, Tatonetti N.
europepmc   +1 more source

The Social Developer: The Future of Software Development [Guest Editors' Introduction] [PDF]

, 2019
Tom Mens, Marcelo Cataldo, Daniela Damian   +2 more
openalex   +1 more source

Agile Software Development [PDF]

, 2013
Meshcheryakov, L.I., Morozova, T.I., Seredinskaya, Olga   +2 more
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Software Development [PDF]

, 2020
openaire   +2 more sources

Enhancing mobile EEG: Software development and performance insights of the DreamMachine. [PDF]

HardwareX
Samimisabet P, Krieger L, De Palol MV, Gün D, Pipa G.   +4 more
europepmc   +1 more source

Developer discussion topics on the adoption and barriers of low code software development platforms. [PDF]

Empir Softw Eng, 2023
Alamin MAA, Uddin G, Malakar S, Afroz S, Haider T, Iqbal A.   +5 more
europepmc   +1 more source

Development of Smart Pavement Design Sensitivity Analysis Software for Asset Management System [PDF]

, 2020
Byungkyu Moon, Jungyong “Joe” Kim, Hosin Lee   +2 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source