Results 171 to 180 of about 7,103,185 (329)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Developer discussion topics on the adoption and barriers of low code software development platforms. [PDF]

open access: yesEmpir Softw Eng, 2023
Alamin MAA   +5 more
europepmc   +1 more source

ICITS'24 - A Systematic Mapping Study on the Use and Development of Research Software

open access: green, 2023
Érica Mourão   +3 more
openalex   +1 more source

Agile Software Development [PDF]

open access: yes, 2013
Meshcheryakov, L.I.   +2 more
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Agile software development one year into the COVID-19 pandemic. [PDF]

open access: yesEmpir Softw Eng, 2022
Ågren P, Knoph E, Berntsson Svensson R.
europepmc   +1 more source

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