Results 201 to 210 of about 6,869,870 (334)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

GrimoireLab: A toolset for software development analytics. [PDF]

open access: yesPeerJ Comput Sci, 2021
Dueñas S   +6 more
europepmc   +1 more source

Software development processes

open access: yesComputer Science Journal of Moldova, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Sustainable software development in science - insights from 20 years of Vanted. [PDF]

open access: yesJ Integr Bioinform
Schreiber F   +7 more
europepmc   +1 more source

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