Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Streamlining medical software development with CARE lifecycle and CARE agent: an AI-driven technology readiness level assessment tool. [PDF]
Hart SN, Day PL, Garcia CA.
europepmc +1 more source
Stakeholders' Perspectives on Partnering to Inform the Software Development Lifecycle of Smartphone Applications for People with Serious Mental Illness: Enhancing the Software Development Lifecycle Through Stakeholder Engagement. [PDF]
Storm M+5 more
europepmc +1 more source
Future development of manufacturing software for machine tool industry.
Akimitsu Nagae
openalex +2 more sources
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
Promoting mental health in the workplace: web software development and validation. [PDF]
Pinhatti EDG+4 more
europepmc +1 more source
Methods for Monitoring Productivity in Applicative Software Development
M. Čičin-Šain
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Detecting the functional interaction structure of software development teams. [PDF]
Zingg C+4 more
europepmc +1 more source