Results 111 to 120 of about 1,880,655 (305)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
ISO-Standardized Requirements Activities for Very Small Entities
, 2010 International audienceThe use of Software Engineering standards may promote recognized and valuable engineering practices for Very Small Entities (VSEs) but these standards do not fit the needs of VSEs.
Ribaud, Vincent, Saliou, Philippe
core +1 more source
SPEM 2.0 extension for pervasive information systems [PDF]
, 2012 Pervasive computing is a research field of computing technology that aims to achieve a new computing paradigm. In this paradigm, the physical environment has a high degree of pervasiveness and availability of computers and other information technology (
Fernandes, José Eduardo +1 more
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Estudio sobre realización y documentación de pruebas software
Maskana, 2015 RESUMEN El presente trabajo describe el proceso realizado y resultados obtenidos al estudiar la documentación técnica de los desarrollos de software (DS) del grupo de investigación en sistemas y tecnologías de la información (STI), grupo adscrito a la ...
Diego Armando Villareal Diaz +2 more
doaj
Integration of Simulink Models with Component-based Software Models
Advances in Electrical and Computer Engineering, 2008 Model based development aims to facilitate the development of embedded control systems by emphasizing the separation of the design level from the implementation level.
MARIAN, N., TOP, S.
doaj +1 more source
NASA's Software Safety Standard [PDF]
NASA (National Aeronautics and Space Administration) relies more and more on software to control, monitor, and verify its safety critical systems, facilities and operations.
Ramsay, Christopher M.
core +1 more source
Sea Level Requirements as Systems Engineering Size Metrics [PDF]
, 2005 The Constructive Systems Engineering Cost Model (COSYSMO) represents a collaborative effort between industry, government, and academia to develop a general model to estimate systems engineering effort. The model development process has benefited from a
Raj, Jatin, Valerdi, Ricardo
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source