Results 111 to 120 of about 1,694,387 (293)
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
An investigation into artificial intelligence based generative computer process planning [PDF]
The process planning function can be further optimized with the introduction of an intelligent software package such as an Artificial Intelligence based Generative Computer Process Planning System.
Tereshkovich, William
core +1 more source
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
Evaluating the Applicability of Requirements Engineering Tools for Distributed Software Development [PDF]
Requirements engineering (RE) is the first part of the software engineering process. It consists of distinct phases in which certain stakeholders deal with the problem of creating and maintaining a systems requirements document.
Geisser, Michael+2 more
core
Integration of Simulink Models with Component-based Software Models
Model based development aims to facilitate the development of embedded control systems by emphasizing the separation of the design level from the implementation level.
MARIAN, N., TOP, S.
doaj +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Development of Interactive Materials by Engineering Students Using the Descartes Applets.
In a degree course such as Forestry Engineering, the general teaching objectives consist of explaining and helping students to understand the principles of Mechanics.
Ayuga Téllez, Esperanza+3 more
core
An investigation of the utility and value of process patterns in the management of software development projects. [PDF]
Pattern theory has engendered much controversy in the field of architecture; yet it has brought new insights to the field of software engineering.
Estabraghy, A., Estabraghy, A.
core
Estudio sobre realización y documentación de pruebas software
RESUMEN El presente trabajo describe el proceso realizado y resultados obtenidos al estudiar la documentación técnica de los desarrollos de software (DS) del grupo de investigación en sistemas y tecnologías de la información (STI), grupo adscrito a la ...
Diego Armando Villareal Diaz+2 more
doaj