Results 71 to 80 of about 1,880,655 (305)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Motorola Secure Software Development Model [PDF]
Journal of Systemics, Cybernetics and Informatics, 2008 In today's world, the key to meeting the demand for improved security is to implement repeatable processes that reliably deliver measurably improved security.
Francis Mahendran, Margaret Nadworny
doaj
Revista Latino-Americana de Enfermagem, 2015 Objective: to report the development of a software to support decision-making for the selection of nursing diagnoses and interventions for children and adolescents, based on the nomenclature of nursing diagnoses, outcomes and interventions of a ...
Kenya de Lima Silva +2 more
doaj +1 more source
Implementación European Credit Transfer System en un curso de Programación en Ingeniería = European Credit Transfer System implementation in an Introduction to Programming Course for a Mechanical Engineering Degree [PDF]
, 2008 Los autores documentan en este artículo el proceso de adaptación a una metodología acorde con los créditos ECTS dentro de una asignatura de introducción a la Programación de ordenadores para ingenieros, equiparable a la que existe en los primeros cursos ...
Bravo Trinidad, José Luis +1 more
core +1 more source
Detecting Coordination Problems in Collaborative Software Development Environments [PDF]
, 2008 Software development is rarely an individual effort and generally involves teams of developers collaborating to generate good reliable code. Among the software code there exist technical dependencies that arise from software components using services ...
Amrit, Chintan, Hillegersberg, Jos van
core +5 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A Pilot Experience with Software Programming Environments as a Service for Teaching Activities
Applied Sciences, 2020 Software programming is one of the key abilities for the development of Computational Thinking (CT) skills in Science, Technology, Engineering and Mathematics (STEM).
Amanda Calatrava Arroyo +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Automation Design and Analysis of the Wing Based on Aerodynamic and Structure Aspect Respectively [PDF]
, 2014 Configuration/Geometry definition, grid generation/mashing, and modeling in wing design and analysis process usually spend much time to support calculation by computer program.
HADI, B. K. (BAMBANG) +3 more
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