Results 181 to 190 of about 1,789,157 (322)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

The study of biosafety risk identification and analysis for facilities in biosafety level 3 laboratories. [PDF]

Front Cell Infect Microbiol
Lv B, Zhou Z, Wang J, Niu Q, Shi Y, Sun Y, Zhao H, Lu D, Fan T, Huang Y.   +9 more
europepmc   +1 more source

Agent-based tool to support collaborative KMS in software maintenance process environment [PDF]

, 2008
Mohd Zali Mohd Nor, Rusli Abdullah, M.H. Selamat, Masitah Ghazali   +3 more
openalex   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

A roadmap for the widespread adoption of frugal microscopes. [PDF]

Nat Commun
Rahmoon MA, Hobson CM, Chew TL, Aaron JS.   +3 more
europepmc   +1 more source

Software maintenance: an analysis of industrial needs and constraints

, 2003
M. Haziza, J.F. Voidrot, Edward O. Minor, L. Pofelski, Sandrine Blazy   +4 more
openalex   +2 more sources

Classifying desirable features of software visualization tools for corrective maintenance [PDF]

, 2008
Mariam Sensalire, Patrick Ogao, Alexandru Telea   +2 more
openalex   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Cost-effectiveness analysis of capecitabine versus active monitoring in stable or responding metastatic colorectal cancer after 16 weeks of first-line therapy. [PDF]

Ann Med
Liu T, Yao R, Tong Z, Dong M, Zhong L.
europepmc   +1 more source