Results 151 to 160 of about 1,536,107 (311)

Software Change Size Measurement: an Exploratory Systematic Mapping Study

open access: yes
Change in software projects can occur through various channels. Customers may request modifications or new features; appraisal activities such as reviews or testing may uncover issues that necessitate adjustments, or products may need to adapt to changes
Tekin, Kuğu   +4 more
core  

Software Size Measurement: Bridging Research and Practice

open access: yes
Despite the availability of software size measures with proven effectiveness, structured characteristics, and reliability, practitioners often favor subjective estimation approaches like story points due to perceived ease and flexibility.
Hacaloglu,T.   +7 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Endoscopic Polyp Size Measurement Using a Laser-Based Sizing Probe: Pilot Study. [PDF]

open access: yesEndosc Int Open
Mahdadi MZ   +13 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Organisational commitment among software developers

open access: yes, 2005
If software developers are to be taken as prototypes of the new knowledge worker, we need look no further for working hypotheses about their attachment to their work and their employing organization than those contained in the human resource management ...
Scholarios, D.M., Baldry, C., Hyman, J.
core  

Geometric Transformation Algorithm for Acetabular Cup Orientation: Converting 2D Radiographic Projections to 3D Spatial Positioning. [PDF]

open access: yesIn Vivo
Aktas G   +8 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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