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Estimation metrics in software projects
A software product that implements a hybrid metric was developed. It articulates relevant characteristics of three estimation metrics in Communication and Information Technology development projects: (i) history points, (ii) use case points, (iii) function points; as a planning strategy to control problems in software projects that tend to last longer ...
Rojas Puentes, M.P.+3 more
openaire +4 more sources
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Software Architecture Coupling Metric for Assessing Operational Responsiveness of Trading Systems [PDF]
The empirical observation that motivates our research relies on the difficulty to assess the performance of a trading architecture beyond a few synthetic indicators like response time, system latency, availability or volume capacity.
Claudiu VINTE
doaj
Design and analysis of hierarchical software metrics [PDF]
Ronald E. Prather
openalex +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
Software metrics for small database applications [PDF]
Sana Abiad+2 more
openalex +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Methodology for validating software metrics
A comprehensive metrics validation methodology is proposed that has six validity criteria, which support the quality functions assessment, control, and prediction, where quality functions are activities conducted by software organizations for the purpose of achieving project quality goals.
openaire +3 more sources