Results 111 to 120 of about 3,700,849 (335)
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva+5 more
wiley +1 more source
Ontology for Software Metrics and Indicators: Building Process and Decisions Taken [PDF]
Luis Olsina, M.A. Martı́n
openalex +1 more source
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
Study on the Evaluation Method of Transmission Gear Rattle Noise based on Energy Fluctuation
The gear rattle noise is analyzed from the perspective of energy fluctuation and a metric named"energy fluctuation metric"is proposed for the evaluation of gear rattle.
Gao Siqi+5 more
doaj
A metrics suite for measuring reusability of software components [PDF]
Hironori Washizaki+2 more
openalex +1 more source
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
Towards a suite of software configuration management metrics [PDF]
Lars Bendix, Lorenzo Borracci
openalex +1 more source
Many researchers have criticized the field of Software Complexity metrics for the lack of testing, verification, and reproducibility of many metrics and case studies that utilized those metrics. This document describes SMF, a tool that can help address some of these concerns, namely by enabling verification of metrics, reproducibility of experiments ...
openaire +2 more sources
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee+9 more
wiley +1 more source
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima+6 more
wiley +1 more source