Results 131 to 140 of about 3,700,849 (335)
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Cross-Project Defect Prediction Using Transfer Learning with Long Short-Term Memory Networks
IET SoftwareWith the increasing number of software projects, within-project defect prediction (WPDP) has already been unable to meet the demand, and cross-project defect prediction (CPDP) is playing an increasingly significant role in the area of software ...
Hongwei Tao +6 more
doaj +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Visualizing metrics on areas of interest in software architecture diagrams [PDF]
, 2009 Heorhiy Byelas, Alexandru Telea
openalex +1 more source
An empirical study on software defect prediction with a simplified metric set [PDF]
Information and Software Technology, 2014 Peng He +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
A methodology for integrating maintainability using software metrics
, 2003 John A. Lewis, Sallie M. Henry
openalex +2 more sources
Evaluation of a Suite of Metrics for Component Based Software Engineering (CBSE) [PDF]
, 2009 V. Lakshmi Narasimhan +2 more
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source