Results 141 to 150 of about 252,658 (290)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Design and Implementation of Component based Metric for Software Complexity Measurement

, 2019
Sonal Gahlot, Rajender Singh Chhillar
openalex   +1 more source

Applying Software Metrics to RNN for Early Reliability Evaluation [PDF]

, 2020
Hao Zhang, Jie Zhang, Ke Shi, Hui Wang
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Defining an approach to empower clinical geneticists to do genomic reanalysis. [PDF]

BMC Med Genomics
Segal MM, McEntagart M, Deng AT, Haworth A, King B, Rogers A, Filby J, Short J, Hash MG, Rives LC, Ezell KM, Undiagnosed Diseases Network, Phillips JA.   +12 more
europepmc   +1 more source

Methods for Calculation and Application of Software Code Metrics: A Systematic Mapping Study

Artem O. Korznikov, N. N. Datsun
openalex   +1 more source

Peer Review #2 of "On the impact of service-oriented patterns on software evolvability: a controlled experiment and metric-based analysis (v0.1)"

, 2019
Justus Bogner, Stefan Wagner, Alfred Zimmermann, M Ali, M Elish, J Bogner, S Wagner, A Zimmermann, J Bogner, A Zimmermann, S Wagner, R Daigneau, T Erl, B Carlyle, C Pautasso, R Balasubramanian, D Falessi, N Juristo, C Wohlin, B Turhan, J Mnch, A Jedlitschka, M Oivo, M Fowler, M Galster, P Avgeriou, J Garzs, F Garca, M Piattini, P Hegeds, D Bn, R Ferenc, T Gyimthy, M Hirzalla, J Cleland-Huang, A Arsanjani, M Host, B Regnell, C Wohlin, A Jedlitschka, M Ciolkowski, D Pfahl, M Kassab, G El-Boussaidi, H Mili, C Mateos, A Zunino, S Misra, D Anabalon, A Flores, T Mccabe, S Newman, J.-P Ostberg, S Wagner, F Palma, L An, F Khomh, N Moha, Y.-G Gueheneuc, M Papazoglou, C Pautasso, E Wilde, M Perepletchikov, C Ryan, K Frampton, Z Tari, M Riaz, T Breaux, L Williams, D Rowe, J Leaney, D Lowe, D Rud, A Schmietendorf, R Dumke, I Salman, A Misirli, N Juristo   +77 more
openalex   +2 more sources

Cross-Project Vulnerability Prediction Based on Software Metrics and Deep Learning

, 2020
Ilias Kalouptsoglou, Miltiadis Siavvas, Dimitrios Tsoukalas, Dionysios Kehagias   +3 more
openalex   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Generating reliable software project task flows using large language models through prompt engineering and robust evaluation. [PDF]

Sci Rep
Sarim M, Masood F, Maheshwari M, Faridi AR, Shamsan AH.   +4 more
europepmc   +1 more source