Results 111 to 120 of about 891,695 (342)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

INTEGRATION PROCESSES QUALITY IN HETEROGENOUS ENVIRONMENTS [PDF]

open access: yes
It presents heterogeneous distributed software applications concept. It describes integration techniques. It defines quality of integration processes regarding heterogeneous environments.
Ion Ivan, Leonard Săcuiu
core  

Software publications and metrics

open access: yes, 2016
Slides presented by Elena Zudilova-Seinstra at the 3:AM conference, 28th - 29th September, Bucharest ...
openaire   +1 more source

Estimation metrics in software projects

open access: yesJournal of Physics: Conference Series, 2018
A software product that implements a hybrid metric was developed. It articulates relevant characteristics of three estimation metrics in Communication and Information Technology development projects: (i) history points, (ii) use case points, (iii) function points; as a planning strategy to control problems in software projects that tend to last longer ...
Rojas Puentes, M.P.   +3 more
openaire   +4 more sources

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Methodology for validating software metrics

open access: yesIEEE Transactions on Software Engineering, 1992
A comprehensive metrics validation methodology is proposed that has six validity criteria, which support the quality functions assessment, control, and prediction, where quality functions are activities conducted by software organizations for the purpose of achieving project quality goals.
openaire   +3 more sources

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