Results 261 to 270 of about 4,534,833 (370)

Comparative assessment of physiochemical metrics for the clustering of adaptive immune receptor repertoires. [PDF]

Nucleic Acids Res
Girgis AA, Huff AL, Davis-Marcisak E, Palmer T, Wang H, Kagohara LT, Montagne JM, Lvovs D, Danilova L, Favorov AV, Schneck J, Bingham Iii CO, Darrah E, Jaffee EM, Zaidi N, Afsari B, Fertig EJ.   +16 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Dysfunctional default mode and visual networks underlie cognitive deficits in dementia with Lewy bodies: a resting-state fMRI study. [PDF]

Front Aging Neurosci
Su Z, Liu M, Kuai J, Yi T, Zheng Y, Bao X, Ji J.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

AutoLEI: A step towards automatic 3D ED data processing. [PDF]

IUCrJ
Wu S, Ma Y.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The Holistic Health and Fitness Management System (H2FMS): a modernised software capability for optimising soldier readiness and performance. [PDF]

BMJ Mil Health
Thompson AG, Rinaldi NA, Smith CL, Bigelman KA.   +3 more
europepmc   +1 more source

Investigating suitability of software process and metrics for statistical process control

, 2020
Ayça Tarhan, Onur Demirörs
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Uncertainty quantification enables reliable deep learning for protein-ligand binding affinity prediction. [PDF]

Sci Rep
Rayka M, Naghavi SS.
europepmc   +1 more source