Results 81 to 90 of about 17,927 (312)

Rigorous software pipeline for clinical somatic mutation analyses of solid tumors [PDF]

, 2023
Ivaylo Stoimenov, Marina Rashyna, Tom Adlerteg, Luís Nunes, Joakim Ekström, Viktor Ljungström, Lucy Mathot, Ian Cheong, Tobias Sjöblom   +8 more
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Implementation of Loop Pipelining and Assignment Inlining in the C-to-HDL Translator

Труды Института системного программирования РАН, 2018
Implementing algorithms for field-programmable gate arrays using a hardware description language is a complex task. Therefore, it would be useful to have a tool that can efficiently translate an algorithm from a high-level language to a hardware ...
Alexey Merkulov, Andrey Belevantsev
doaj  

A review of High Performance Computing foundations for scientists

, 2012
The increase of existing computational capabilities has made simulation emerge as a third discipline of Science, lying midway between experimental and purely theoretical branches [1, 2].
Cramer C. J., Dongarra J., Dror R. O., Goldberg D., Hager G., Haoqiang J., Hennessy J. L., Marx D., Moore G., PABLO E. IBÁÑEZ, PABLO GARCÍA-RISUEÑO, Wilkinson B., Woo D. H.   +12 more
core   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

End-to-End Analysis Automation over Distributed Resources with Luigi Analysis Workflows [PDF]

EPJ Web of Conferences
In particle physics, workflow management systems are primarily used as tailored solutions in dedicated areas such as Monte Carlo production. However, physicists performing data analyses are usually required to steer their individual, complex workflows ...
Rieger Marcel
doaj   +1 more source

N-Dimensional Perfect Pipelining [PDF]

, 1992
In this paper, we introduce a technique to parallelize nested loops at the fine grain level. It is a generalization of Perfect Pipelining which was developed to parallelize a single-nested loop at the fine grain level.
Kim, Ki-Chang, Nicolau, Alexandru
core  

Sam2bam: High-Performance Framework for NGS Data Preprocessing Tools

, 2016
This paper introduces a high-throughput software tool framework called {\it sam2bam} that enables users to significantly speedup pre-processing for next-generation sequencing data.
Cheng, Yinhe, Ogasawara, Takeshi, Tzeng, Tzy-Hwa Kathy   +2 more
core   +4 more sources

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

COLORING OF GRAY-SCALE IMAGE USING FPGA

Journal of Engineering
The image processing is one from the most powerful fields in the modern DSP techniques; also it has wide range of applications this day such as image compression, filtering and coloring.
Ammar A. Hassan
doaj   +1 more source