Results 171 to 180 of about 2,162,371 (314)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A roadmap for a comparison framework for an adaptable software process improvement framework in small software companies [PDF]

Annals of computer science and information systems, 2019
Micheal Tuape, Yirsaw Ayalew
doaj   +1 more source

Effect of Laser Power on the Corrosion and Wear Resistance of Laser Cladding TC4 Alloy. [PDF]

Materials (Basel)
Li X, Zhao S, Zhang K, Cui L, Guo S, Zheng B, Cui Y, Chen Y, Zhao Y, Xu C.   +9 more
europepmc   +1 more source

Trends in the Research on Software Process Improvement in Scandinavia.

, 2001
Karlheinz Kautz
openalex   +1 more source

Views, Experiences and Uncertainties on the Benefits of SPI from the Book- “Software Process Improvement-Practical Guidelines for Business Success”

, 2018
Reddi Prasadu
openalex   +1 more source

Software Process Improvement by SPICE Methodology

Journal of Information and Organizational Sciences, 1999
In this paper the results of SPlCE methodology implementation are described - the concepts and the organisations of SPICE, SPICE process model architecture, and the matter of the practical use of a SPlCE methodology in process assessment and improvement.
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Software Process Improvement:Where Is the Evidence?

, 2016
Software process improvement (SPI) is around for decades: frameworks are proposed, success factors are studied, and experiences have been reported. However, the sheer mass of concepts, approaches, and standards published over the years overwhelms practitioners as well as researchers. What is out there? Are there new emerging approaches?
Kuhrmann, Marco, Konopka, Claudia, Nellemann, Peter, Diebold, Philipp, Münch, Jürgen   +4 more
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Software Process Improvement Framework

, 2014
Many software development organizations today are keen on improving their software development processes in order to develop software products faster, cheaper or better. For that reason, Software Process Improvement (SPI) has received significant attention from the research community over the last few decades. Process maturity models have become widely
openaire   +1 more source