Results 171 to 180 of about 1,924,275 (351)

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Using an Expert Panel to Validate the Malaysian SMEs-Software Process Improvement Model (MSME-SPI)

open access: green, 2021
Malek Ahmad Almomani   +6 more
openalex   +2 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Increasing hospital administrative efficiency via optimized office automation systems: A PDCA cycle approach. [PDF]

open access: yesPLoS One
Lu R   +11 more
europepmc   +1 more source

Enabling Developer Productivity with Software Process Improvement.

open access: green, 2021
Reed Milewicz   +6 more
openalex   +2 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Developing SPIM-TA: a maturity-level framework for systematic process improvement in software testing automation

open access: yesAin Shams Engineering Journal
The growing complexity and demands for high-quality software underlined the need for robust automated software testing frameworks. However, lack of skilled personnel, cost of testing automation, and maintenance of script along with others oppose the ...
Muhammad Faisal Abrar   +6 more
doaj  

Home - About - Disclaimer - Privacy