Results 31 to 40 of about 1,851,016 (268)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Analysis and Comparision of Waterfall Model and Agile Approach in Software Projects
Online Academic Journal of Information Technology, 2023 Looking at the history of civilization from past to present, the concepts of project and project management are frequently encountered. Thanks to project management, businesses can work target-oriented, provide high motivation, facilitate internal ...
Ceyda Ünal +2 more
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Journal of Advanced Computing Systems, 2023 This study presents a comprehensive framework for real-time AI-driven attribution modeling to optimize dynamic budget allocation in the U.S. small appliance e-commerce sector.
Me Sun, Zhen Feng, Pengfei Li
doaj +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Machine learning-based B2C software project success prediction model in Indonesia
IJAIN (International Journal of Advances in Intelligent Informatics)The success of a software project is a crucial factor in the information technology industry, but it is often difficult to predict due to its complexity and high dynamics.
Rudi Setiawan, Titik Khawa Abdul Rahman
doaj +1 more source
International Journal of Information Systems and Project Management, 2023 Software project teams (SPTs) are critical stakeholders. Their contribution in successful delivery of software projects is unquestionable. However, the empirical evidence of their importance seems to exist on paper only, as software project managers ...
Robert Hans, Ernest Mnkandla
doaj
A Software Projects Crest and Trough in Pakistan: A Management Spectrum
Sukkur IBA Journal of Computing and Mathematical Sciences, 2023 Software industry has become as popular factor in the progress triumph of every country. Software project management techniques are significantly applicable in the development cycle of software projects.
Salwa iqbal +2 more
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source