Results 41 to 50 of about 1,937,401 (263)
CREATIVITY RISK IN SOFTWARE PROJECTS
Research on Enterprise in Modern Economy Theory and Practice, 2018 Creativity risk appears when the goals related to creativity are not achieved or unwanted consequences of using creativity methods take place. This paper deals with creativity risk using dimensions of directed creativity and risk management categories ...
Anna Bobkowska
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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A Software Projects Crest and Trough in Pakistan: A Management Spectrum
Sukkur IBA Journal of Computing and Mathematical Sciences, 2023 Software industry has become as popular factor in the progress triumph of every country. Software project management techniques are significantly applicable in the development cycle of software projects.
Salwa iqbal +2 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Entropy, 2015 Complexity is an important factor throughout the software life cycle. It is increasingly difficult to guarantee software quality, cost and development progress with the increase in complexity.
Rong Jiang
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
A New Architecture Based on Artificial Neural Network and PSO Algorithm for Estimating Software Development Effort [PDF]
Journal of Advances in Computer Engineering and Technology, 2018 Software project management has always faced challenges that have often had a great impact on the outcome of projects in future. For this, Managers of software projects always seek solutions against challenges.
Amin Moradbeiky, Amid Khatibi Bardsiri
doaj
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
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